Objectives: To develop a concise screening instrument for early identification of employees at risk for sickness absence due to psychosocial health complaints. Methods: Data from the Maastricht Cohort Study on "Fatigue at Work" were used to identify items to be associated with an increased risk of sickness absence. The analytical procedures univariate logistic regression, backward stepwise linear regression, and multiple logistic regression were successively applied. For both men and women, sum scores were calculated, and sensitivity and specificity rates of different cut-off points on the screening instrument were defined. Results: In women, results suggested that feeling depressed, having a burnout, being tired, being less interested in w...