BACKGROUND AND OBJECTIVES: Neurofilament light chain (NfL) is a biomarker for neuroaxonal damage and has been found to be elevated proportionally to the degree of neuronal damage in neurologic diseases. The objective of this study was to determine the prognostic accuracy of NfL concentrations on unfavorable outcome in adults with community-acquired bacterial meningitis. METHODS: We measured NfL concentration CSF samples from a prospective cohort study of adults with community-acquired bacterial meningitis in The Netherlands and determined associations between NfL CSF concentrations, clinical characteristics, and outcome in multivariate analyses. We identified independent predictors of an unfavorable outcome (Glasgow Outcome Scale scores 1-4...
Objective: To aid diagnostics, patient stratification and studies seeking to find treatments for the...
Objective: To evaluate cerebrospinal fluid (CSF) and serum neurofilament light chain (NfL) levels in...
Motor neuron disease (MND) is a rare group of disorders characterized by degeneration of motor neuro...
BACKGROUND AND OBJECTIVES: Neurofilament light chain (NfL) is a biomarker for neuroaxonal damage and...
Diagnosing central nervous system (CNS) infections quickly is often difficult. Neurofilament light c...
Background Pneumococcal meningitis (PM) remains a global public health concern and affects all age ...
Importance: Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a number o...
Background and ObjectivesDeterminants of disease activity and prognosis are limited in anti-NMDA rec...
Importance: Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a number o...
Neurofilament light chain (NFL) levels reflect axonal damage in different inflammatory and neurodege...
OBJECT: Routine microbiological and chemical analysis of cerebrospinal fluid (CSF) is often performe...
Key PointsQuestionHow do levels of neurofilament light in cerebrospinal fluid (cNfL) compare between...
Introduction: Neurofilament light chain (NfL) is a promising biomarker in neurodegenerative diseases...
OBJECTIVES: Central nervous system (CNS) infections are common causes of morbidity and mortality wor...
OBJECTIVES: We hypothesized that CSF neurofilament light (NFL) levels would be elevated in dementias...
Objective: To aid diagnostics, patient stratification and studies seeking to find treatments for the...
Objective: To evaluate cerebrospinal fluid (CSF) and serum neurofilament light chain (NfL) levels in...
Motor neuron disease (MND) is a rare group of disorders characterized by degeneration of motor neuro...
BACKGROUND AND OBJECTIVES: Neurofilament light chain (NfL) is a biomarker for neuroaxonal damage and...
Diagnosing central nervous system (CNS) infections quickly is often difficult. Neurofilament light c...
Background Pneumococcal meningitis (PM) remains a global public health concern and affects all age ...
Importance: Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a number o...
Background and ObjectivesDeterminants of disease activity and prognosis are limited in anti-NMDA rec...
Importance: Neurofilament light protein (NfL) is elevated in cerebrospinal fluid (CSF) of a number o...
Neurofilament light chain (NFL) levels reflect axonal damage in different inflammatory and neurodege...
OBJECT: Routine microbiological and chemical analysis of cerebrospinal fluid (CSF) is often performe...
Key PointsQuestionHow do levels of neurofilament light in cerebrospinal fluid (cNfL) compare between...
Introduction: Neurofilament light chain (NfL) is a promising biomarker in neurodegenerative diseases...
OBJECTIVES: Central nervous system (CNS) infections are common causes of morbidity and mortality wor...
OBJECTIVES: We hypothesized that CSF neurofilament light (NFL) levels would be elevated in dementias...
Objective: To aid diagnostics, patient stratification and studies seeking to find treatments for the...
Objective: To evaluate cerebrospinal fluid (CSF) and serum neurofilament light chain (NfL) levels in...
Motor neuron disease (MND) is a rare group of disorders characterized by degeneration of motor neuro...