Comparative Antidiabetic Activity of Aqueous, Alcoholic and Hydro Alcoholic Leaf Extract of Mangiferaindica using Various In Vitro Models

An extensive research in ethno pharmacology has taken place throughout the world. The leaves of Mangiferaindica was traditionally claimed for a large number of pharmacological actions and medicinal uses. In present investigation, the COMPARATIVE INVITRO ANTIDIABETIC study revealed that the among the various extracts such as aqueous, alcoholic, and hydro alcoholic extracts of dried leaves of Mangiferaindica the aqueous extract is found to have more ANTIDIABETIC action when compared to the other extracts. The antidiabetic activity may be attributed due to the phytoconstituents present in it. The present study offered a scientific proof to the traditional use of Mangiferaindica. Further, phytochemical studies are needed to isolate the active compounds responsible for these pharmacological activities. The comparative study showed that the hydro alcoholic extract of Mangiferaindica leaves has more ANTIDIABETIC activity when compared to aqueous and alcoholic extracts. The present study is attempted to develop a novel plant based antidiabetic drug. Extensive research will be needed to determine the individual component responsible for the antidiabetic activity and molecular mechanism responsible for the same