Non-Progressive CRMP-5 Associated Paraneoplastic Retinopathy

Paraneoplastic retinitis typically presents with gradual painless visual loss and photosensitivity. Autoimmunity against recoverin is known to cause paraneoplastic retinitis whereas collapsin response mediator protein (CRMP-5), a 62-kDa protein that guides developing axons, is typically associated with paraneoplastic optic neuropathy. Its expression suggests involvement in neuronal and glial development1. We treated a woman withbreast cancer who developed a non-progressive paraneoplastic perifoveal retinitis Identified by the presence of CRMP-5