A comprehensive review on the phytochemical constituents, antioxidant and anticancer properties of piper sarmentosum

Introduction: Piper sarmentosum is a herbaceous plant that belongs to the Piperaceae family and possesses antioxidant and anticancer properties due to its phytochemical compositions. It grows abundantly in Southeast Asia and is widely explored in the ethnomedicinal study. Method: This paper reviews previous scientific research data on P. sarmentosum on its phytochemical constituents and antioxidant and anticancer properties. Related scientific articles were searched through academic search engines, including Elsevier, Science Direct, Google Scholar, and IOP Scinotes, where the literatures were reviewed thoroughly. Results: The findings from the study have concluded that P. sarmentosum contains essential oils and flavonoids. Extensive reports on its antioxidant potential were also recorded, where P. sarmentosum was found to reduce free radicals. Researchers discovered that anticancer activities were exhibited against several cancer cell lines, including HepG2, HT-29, MCF-7, HeLa, MDA-MB-231, and HK-1. From the studied literatures, it can be concluded that the phytochemicals in P. sarmentosum contribute to its antioxidant and anticancer properties. Conclusion: This research provides comprehensive and updated information on P. sarmentosum’s phytochemical constituents. These antioxidant and anticancer properties and antioxidant and anticancer properties that could be used as references for further investigation of P. sarmentosum in the pharmacological study