Evaluation of bioavailability of three extracts of a less known ethno-medicinal plant, Thottea tomentosa from Assam

55-64Plants of the genus Thottea have been established as wild ethno-medicinal plants. The plant, Thottea tomentosa also has the illness recuperative property. However, there are no such reports so far on the solvent polarity based performances of the plant. Hence, the current work deals with the assessment of bioavailabilities like qualitative phyto-chemical screening, total phenol contents, total flavonoid contents, antioxidant efficiency, and antimicrobial efficiency using three solvents of diverse polarities like hexane, chloroform, and methanol. The phenolic compositions of methanol extract of stem and leaf; 374.99±3.84 and 260.55±4.00 mg GAE per gram of dry weight of extract respectively and correlate by linking antioxidant activities of methanol extract of the stem and leaf (DPPH; IC50 202.39±0.92 and 254.37±1.47 μg/mL respectively). Thus, probable antimicrobial activities of methanol extract of stem and leaf were also study, than that of other extracts. Methanol stem extract against the microbes; Bacillus subtilis (MTCC 1427), Escherichia coli (MTCC 1195), Pseudomonas aeruginosa (MTCC 1688), Staphylococcus aureus susp. aureus (MTCC 1430), Streptococcus pneumonie (MTCC 2672), Aspergillus niger (Lab isolates) and Candida albicans (MTCC 4748) exhibited highest zone of inhabitation (ZOI). Therefore, these results indicate that T. tomentosa can be satisfying the dietetic demand for the food and drug production