Continuous infusion (CON) of fosfomycin has been proposed as potentially advantageous in certain clinical scenarios. However, no clinical data on the pharmacokinetics (PK) of fosfomycin after CON are available to date. This study aimed to investigate the PK of fosfomycin after CON and compare it with intermittent infusion (INT) of fosfomycin. A randomized two-way crossover study including 8 healthy male volunteers was performed. Each subject received fosfomycin as INT of 8 g over 30 min every 8 h and, separated by a washout period, as CON of 1 g/h preceded by a loading dose of 8 g over 30 min. PK sampling was performed for 18 and 24 h in the CON and INT groups, respectively. Fosfomycin was generally well tolerated. However, 2 out of 8 subje...
Fosfomycin has become an attractive treatment alternative for urinary tract infections (UTIs) due to...
Fosfomycin is a broad-spectrum antibiotic which is established as therapy for uncomplicated lower ur...
Seyed MohammadReza Hashemian,1,2 Zinat Farhadi,3 Tayebeh Farhadi1 1Chronic Respiratory Diseases Res...
This study describes the population pharmacokinetics of fosfomycin in critically ill patients. In th...
4noFosfomycin (FOS) administered intravenously has been recently rediscovered for the treatment of s...
textabstractFosfomycin has emerged as a potential therapy for multidrug-resistant bacterial infectio...
The intravenous (IV) formulation of fosfomycin has been re-introduced lately in clinical practice ma...
Fosfomycin has emerged as a potential therapy for multidrug-resistant bacterial infections. In most ...
Objectives: To assess the pharmacokinetics and tissue penetration of fosfomycin in obese and non-obe...
To describe the population pharmacokinetics of fosfomycin for patients with bacteraemic urinary trac...
The aim of this study was to investigate the pharmacokinetics of multiple-dose intravenous (i.v.) f...
Objectives: Fosfomycin is increasingly being prescribed for treatment of uncomplicated urinary tract...
Fosfomycin is gaining interest in the treatment of complex osteoarticular infections (OI) due to mul...
Objectives: To evaluate the pharmacokinetics and clinical effectiveness of IV and oral fosfomycin tr...
Fosfomycin has become an attractive treatment alternative for urinary tract infections (UTIs) due to...
Fosfomycin has become an attractive treatment alternative for urinary tract infections (UTIs) due to...
Fosfomycin is a broad-spectrum antibiotic which is established as therapy for uncomplicated lower ur...
Seyed MohammadReza Hashemian,1,2 Zinat Farhadi,3 Tayebeh Farhadi1 1Chronic Respiratory Diseases Res...
This study describes the population pharmacokinetics of fosfomycin in critically ill patients. In th...
4noFosfomycin (FOS) administered intravenously has been recently rediscovered for the treatment of s...
textabstractFosfomycin has emerged as a potential therapy for multidrug-resistant bacterial infectio...
The intravenous (IV) formulation of fosfomycin has been re-introduced lately in clinical practice ma...
Fosfomycin has emerged as a potential therapy for multidrug-resistant bacterial infections. In most ...
Objectives: To assess the pharmacokinetics and tissue penetration of fosfomycin in obese and non-obe...
To describe the population pharmacokinetics of fosfomycin for patients with bacteraemic urinary trac...
The aim of this study was to investigate the pharmacokinetics of multiple-dose intravenous (i.v.) f...
Objectives: Fosfomycin is increasingly being prescribed for treatment of uncomplicated urinary tract...
Fosfomycin is gaining interest in the treatment of complex osteoarticular infections (OI) due to mul...
Objectives: To evaluate the pharmacokinetics and clinical effectiveness of IV and oral fosfomycin tr...
Fosfomycin has become an attractive treatment alternative for urinary tract infections (UTIs) due to...
Fosfomycin has become an attractive treatment alternative for urinary tract infections (UTIs) due to...
Fosfomycin is a broad-spectrum antibiotic which is established as therapy for uncomplicated lower ur...
Seyed MohammadReza Hashemian,1,2 Zinat Farhadi,3 Tayebeh Farhadi1 1Chronic Respiratory Diseases Res...