Limb rescue: a new autologous-peripheral blood mononuclear cells technology in critical limb ischemia and chronic ulcers
- De Angelis, B
- Gentile, P
- Orlandi, F
- Bocchini, I
- Di Pasquali, C
- Agovino, A
- Gizzi, C
- Patrizi, F
- Scioli, MG
- Orlandi, A
- Cervelli, V
DOIAbstract
Therapeutic angiogenesis by autologous-peripheral blood mononuclear cells (A-PBMNC) implantation has been shown to be a safe and effective treatment for critical limb ischemia (CLI). We herein report our investigation of the long-term efficacy of implantation of A-PBMNC produced by selective filtration to treat patients with CLI, for which surgical bypass and/or percutaneous transluminal angioplasty are not possible
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