We have studied the effect of acute and chronic lithium treatment on the activity of striatal neurons recorded from corticostriatal slices. Under control conditions, tetanic stimulation of glutamatergic corticostriatal terminals caused long-term depression (LTD) of excitatory synaptic potentials. Acute lithium treatment did not affect the peak of the induction phase, but it reduced the following phases of LTD. LTD was completely blocked in slices obtained from rats chronically injected with LiCl. Lithium treatment failed to affect the intrinsic membrane properties of striatal neurons and the presynaptic inhibitory effects of carbachol and t-ACPD. We suggest that the lithium-induced blockade of LTD may contribute to the therapeutic action of...
Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more years, a...
Extracellular and intracellular recordings were obtained from striatal neurons in a brain slice prep...
AbstractThe neuroprotective effects of lithium, a mood stabilizer, against glutamate-induced excitot...
We have studied the effect of acute and chronic lithium treatment on the activity of striatal neuron...
International audienceBackground: Bipolar disorder is characterized by cyclical alternation between ...
The therapeutic action of lithium in affective disorders is still unclear. One effect of lithium is ...
BACKGROUND: Increasing and consistent findings of structural and functional abnormalities in patient...
Increment of cyclic AMP in tissue slices in response to noradrenaline and dopamine stimulation was s...
Lithium is the most commonly used drug for the treatment of manic- depressive illness. The precise m...
Lithium has been used for over half a century for the treatment of bipolar disorder as the archetypa...
The effect of tetanic activation of corticostriatal glutamatergic fibers was studied in striatal sli...
Friedman, Eitan and Frank D. Yocca: The effect of chronic delayed the peak of the diurnal cycle of N...
Thiocolchicoside (TCC) is used clinically for its muscle relaxant, anti-inflammatory, and analgesic ...
Lithium, an effective treatment for mania and the preven-tion of recurrent episodes of both mania an...
In the present study, we employed in vivo microdialysis in the frontal cortex of the awake rat to in...
Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more years, a...
Extracellular and intracellular recordings were obtained from striatal neurons in a brain slice prep...
AbstractThe neuroprotective effects of lithium, a mood stabilizer, against glutamate-induced excitot...
We have studied the effect of acute and chronic lithium treatment on the activity of striatal neuron...
International audienceBackground: Bipolar disorder is characterized by cyclical alternation between ...
The therapeutic action of lithium in affective disorders is still unclear. One effect of lithium is ...
BACKGROUND: Increasing and consistent findings of structural and functional abnormalities in patient...
Increment of cyclic AMP in tissue slices in response to noradrenaline and dopamine stimulation was s...
Lithium is the most commonly used drug for the treatment of manic- depressive illness. The precise m...
Lithium has been used for over half a century for the treatment of bipolar disorder as the archetypa...
The effect of tetanic activation of corticostriatal glutamatergic fibers was studied in striatal sli...
Friedman, Eitan and Frank D. Yocca: The effect of chronic delayed the peak of the diurnal cycle of N...
Thiocolchicoside (TCC) is used clinically for its muscle relaxant, anti-inflammatory, and analgesic ...
Lithium, an effective treatment for mania and the preven-tion of recurrent episodes of both mania an...
In the present study, we employed in vivo microdialysis in the frontal cortex of the awake rat to in...
Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more years, a...
Extracellular and intracellular recordings were obtained from striatal neurons in a brain slice prep...
AbstractThe neuroprotective effects of lithium, a mood stabilizer, against glutamate-induced excitot...