During the normalization phase of COVID-19 epidemic, it is gradually reverted to use building space, especially for office. Prevention of airborne pollutant has emerged as a major challenge. Ventilation strategies can mitigate the spread of airborne disease in indoor environment, such as increasing ventilation rate, modifying ventilation mode, etc. The larger ventilation rate can lead to higher energy consumption may not effectively reduce infection risk. The potential of ventilation modes for COVID-19 control should be explored. Furthermore, it is necessary to adopt low-cost strategies, such as physical barrier, to increase the prevention efficiency while combining the ventilation system. This study was to investigate the impact of physica...