Activating mutations in the K-ras oncogene mainly occur in codons 12 and 13 and may be predictive of response to drugs directly linked to the K-ras signaling pathway, such as panitumumab and cetuximab
Background: Several studies demonstrated that K-Ras codon 12 and 13 mutations in tumor samples can p...
BACKGROUND: Mutations involving the oncogene K-ras in colorectal cancer may be related to tumor aggr...
International audienceBackgroundOverall survival of metastatic colorectal cancer (mCRC) patients has...
Activating mutations in the K-ras oncogene mainly occur in codons 12 and 13 and may be predictive of...
The K-ras gene is frequently mutated in colorectal cancer and has been associated with tumor initiat...
BACKGROUND: Response to EGFR-targeted therapies in colorectal cancer patients has been convincingly ...
Abstract.-Colorectal cancer (CRC) is a disease of the large intestine and regarded as a multistep pr...
Background: K-ras mutations, one of the earliest events observed in colorectal carcinogenesis, are m...
Background. Colorectal cancer (CRC) is one of the most common types of cancer, affecting 3 - 5% of t...
BACKGROUND: Mutations at codons 12, 13, and 61 of the ras genes have been found in a variety of huma...
Background and Aim: Colorectal cancer (CRC) is one of the leading malignancies worldwide. CRC has b...
K-ras oncogene mutations in sporadic colorectal cancer in The Netherlands Cohort Study.Brink M, de G...
Background: Several studies demonstrated that K-Ras codon 12 and 13 mutations in tumor samples can p...
BACKGROUND: Mutations involving the oncogene K-ras in colorectal cancer may be related to tumor aggr...
International audienceBackgroundOverall survival of metastatic colorectal cancer (mCRC) patients has...
Activating mutations in the K-ras oncogene mainly occur in codons 12 and 13 and may be predictive of...
The K-ras gene is frequently mutated in colorectal cancer and has been associated with tumor initiat...
BACKGROUND: Response to EGFR-targeted therapies in colorectal cancer patients has been convincingly ...
Abstract.-Colorectal cancer (CRC) is a disease of the large intestine and regarded as a multistep pr...
Background: K-ras mutations, one of the earliest events observed in colorectal carcinogenesis, are m...
Background. Colorectal cancer (CRC) is one of the most common types of cancer, affecting 3 - 5% of t...
BACKGROUND: Mutations at codons 12, 13, and 61 of the ras genes have been found in a variety of huma...
Background and Aim: Colorectal cancer (CRC) is one of the leading malignancies worldwide. CRC has b...
K-ras oncogene mutations in sporadic colorectal cancer in The Netherlands Cohort Study.Brink M, de G...
Background: Several studies demonstrated that K-Ras codon 12 and 13 mutations in tumor samples can p...
BACKGROUND: Mutations involving the oncogene K-ras in colorectal cancer may be related to tumor aggr...
International audienceBackgroundOverall survival of metastatic colorectal cancer (mCRC) patients has...