BDNF Val66Met polymorphism is associated with aggressive behavior in schizophrenia
- Spalletta, G
- Morris, D
- Angelucci, F
- Rubino, I
- Spoletini, I
- Bria, P
- Martinotti, G
- Siracusano, A
- Bonaviri, G
- Bernardini, S
- Caltagirone, C
- Bossù, P
- Donohoe, G
- Gill, M
- Corvin, A
Publication date
October 2010
DOI Publisher
elsevier ISSN
0924-9338 Citation count (estimate)
40Abstract
Brain-derived neurotrophic factor (BDNF) gene variants may potentially influence behaviour. In order to test this hypothesis, we investigated the relationship between BDNF Val66Met polymorphism and aggressive behaviour in a population of schizophrenic patients. Our results showed that increased number of BDNF Met alleles was associated with increased aggressive behaviour
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