Long-term effectiveness of presacral neurectomy for the treatment of severe dysmenorrhea due to endometriosis

Study Objective. To assess the long-term effectiveness of presacral neurectomy (PSN) in women with severe dysmenorrhea due to endometriosis treated with conservative laparoscopic surgical intervention. Design. Randomized, controlled trial (Canadian Task Force classification I). Setting. University-affiliated department of obstetrics and gynecology. Patients. One hundred forty-one sexually active women of reproductive age. Intervention. Conservative laparoscopic surgery without (group A) or with (group B) PSN. Measurements and Main Results. At entry and 24-months after surgical procedures, cure rates; frequency and severity of dysmenorrhea, dyspareunia, and chronic pelvic pain; and quality of life were evaluated. At follow-up visit, the cure rate was significantly (P<0.05) higher in group B (83.3%) than in group A (53.3%). The frequency and severity of dysmenorrhea, dyspareunia, and chronic pelvic pain were significantly (P<0.05) lower in both groups compared with baseline values, and only severity was significantly (P<0.05) lower in group B. A significant (P<0.05) improvement in quality of life was observed after surgery in both groups and was significantly (P