Add to ORKGNuclear factor κB (NFκB) is a transcription factor that plays an important role in carcinogenesis as well as in the regulation of inflammatory response. NFκB is constitutively expressed in tumours where it induces the expression of genes which promote cell proliferation, apoptotic events, angiogenesis, invasion and metastasis. Furthermore, many cancer cells show aberrant or constitutive NFκB activation that mediates resistance to chemo- and radio-therapy. Therefore, the inhibition of NFκB activity appears a potential therapeutic strategy for cancer treatment. In this review, we focus on the role of NFκB in carcinogenesis and summarize actual inhibitors of NFκB that could be potential therapeutic target in cancer therapy
Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied female d...
Nuclear Factor-kappa B (NF-κB) is a transcription factor family that regulates a large number of gen...
Multidrug resistance (MDR), of the innate and acquired types, is one of major problems in treating t...
Nuclear factor κB (NFκB) is a transcription factor that plays an important role in carcinogenesis as...
Nuclear factor κB (NFκB) is a transcription factor that plays an important role in carcinogenesis as...
Persistent activation of the pro-inflammatory transcription factor nuclear factor-κB (NF-κB) is freq...
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is responsible for the regula...
Transcription factor NF-κB has been extensively studied for its varied roles in cancer development s...
The transcription factor nuclear factor (NF)-κB is activated in certain cancers and in response to c...
Transcription factors of the nuclear factor κB (NF-κB) family are central coordinating regulators of...
The transcription factor nuclear factor kappa B (NF-κB) has attracted increasing attention in the fi...
AbstractNumerous lines of investigation suggest that nuclear factor NF-κB, a proinflammatory transcr...
Nuclear factor-κB (NF-κB) is a transcription factor that plays a crucial role in various biological ...
Intrinsic or acquired resistance to chemotherapeutic agents is a common phenomenon and a major chall...
Transcription factors of the NF-κB family are driven by many inflammatory stimuli and activate expre...
Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied female d...
Nuclear Factor-kappa B (NF-κB) is a transcription factor family that regulates a large number of gen...
Multidrug resistance (MDR), of the innate and acquired types, is one of major problems in treating t...
Nuclear factor κB (NFκB) is a transcription factor that plays an important role in carcinogenesis as...
Nuclear factor κB (NFκB) is a transcription factor that plays an important role in carcinogenesis as...
Persistent activation of the pro-inflammatory transcription factor nuclear factor-κB (NF-κB) is freq...
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is responsible for the regula...
Transcription factor NF-κB has been extensively studied for its varied roles in cancer development s...
The transcription factor nuclear factor (NF)-κB is activated in certain cancers and in response to c...
Transcription factors of the nuclear factor κB (NF-κB) family are central coordinating regulators of...
The transcription factor nuclear factor kappa B (NF-κB) has attracted increasing attention in the fi...
AbstractNumerous lines of investigation suggest that nuclear factor NF-κB, a proinflammatory transcr...
Nuclear factor-κB (NF-κB) is a transcription factor that plays a crucial role in various biological ...
Intrinsic or acquired resistance to chemotherapeutic agents is a common phenomenon and a major chall...
Transcription factors of the NF-κB family are driven by many inflammatory stimuli and activate expre...
Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied female d...
Nuclear Factor-kappa B (NF-κB) is a transcription factor family that regulates a large number of gen...
Multidrug resistance (MDR), of the innate and acquired types, is one of major problems in treating t...