Starfish saponins, 45. Novel sulfated steroidal glycosides from the starfish Astropecten scoparius

Five sulfated steroidal glycosides were isolated from the aq. exts. of the whole bodies of the starfish A. scoparius. One of them was identified as indicoside B, a sulfated steroidal xylofuranoside previously isolated from A. indicus, and the remaining 4 are new compds. Three of them, scopariosides A, B, and C (I, II, and III, resp.) have the same (24SS)-5a-cholestane-3β,6α,8,15β,24-pentaol aglycon as indicoside B but differ in the sugar moieties. The aglycon is also present in the aq. exts. as 24-O-sulfate deriv. The 4th new glycoside, scoparioside D (IV) was also identified. These glycosides are accompanied by 4 known polyhydroxysteroids and 1 known asterosaponin, the hexaglycoside marthasteroside A1