Alternative approach for the synthesis of chiral b-keto sulfoxides by furylhydroperoxides enantioselective oxidations

Enantiomerically enriched beta-keto sulfoxides are obtainable by an alternative method to the classical reaction of the enantiomerically pure alpha-sulfinyl anion with esters or by Andersen's synthesis, through Sharpless modified kinetic resolution of racemic beta-keto sulfoxides. High e.e.s are achieved by combining asymmetric oxidation and kinetic resolution using furylhydroperoxides as oxidant