Photodynamic therapy (PDT) is a non-invasive therapeutic modality used in a number of diseases including psoriasis, age-related macular degeneration and cancer. It involves the systemic or topic administration of a photosensitizer, followed by irradiation with light. The activated photosensitizer converts oxygen to singlet oxygen and/or reactive oxygen species (ROS) which lead to cell death and tissue necrosis. One aim of PDT research is the discovery of new photosensitizers possessing minimal dark cytotoxicity, high photodynamic properties, improved pharmacokinetics, preferential retention in diseased instead of healthy tissues, chemical stability and a good cellular uptake (1). We recently focused our efforts on pheophorbide a (Pba), a ch...
Abstract: Photodynamic therapy (PDT) was discovered more than 100 years ago, and has since become a ...
Photodynamic therapy (PDT) is based on the use of a photosensitizing agent such as porphyrins, altho...
Photodynamic therapy (PDT) has attracted widespread attention due to its potential in the treatment ...
Photodynamic therapy (PDT) is a non-invasive therapeutic modality used in a various number of diseas...
The design of new photosensitizers with enhanced phototoxicity and pharmacokinetic properties remain...
Pheophorbide a (Pba) is a chlorophyll catabolite that has been proposed as photosensitizer in photod...
Pheophorbide a (Pba) has been pegylated to methoxypolyethylene glycol (mPE G-Pba) to produce a solub...
The design of new photosensitizers with enhanced phototoxicity and pharmacokinetic properties remain...
Pheophorbide a (Pba) is a chlorophyll catabolite that has been proposed as photosensitizer in photod...
Photodynamic therapy (PDT) is an approved but under-development modality for cancer therapy. Convent...
Pheophorbide-a derivatives have been reported to be potential photosensitizers for photodynamic ther...
Abstract Background Photodynamic therapy (PDT) is photo-treatment of malignant or benign diseases us...
Summary Photosensitizers in photodynamic therapy allow for the transfer and trans-lation of light en...
Photodynamic therapy (PDT) is a non-invasive and tumour-specific therapy. Photosensitizers (PSs) (es...
Photodynamic therapy (PDT) utilises light, oxygen and organic macrocycles, called photosensitisers, ...
Abstract: Photodynamic therapy (PDT) was discovered more than 100 years ago, and has since become a ...
Photodynamic therapy (PDT) is based on the use of a photosensitizing agent such as porphyrins, altho...
Photodynamic therapy (PDT) has attracted widespread attention due to its potential in the treatment ...
Photodynamic therapy (PDT) is a non-invasive therapeutic modality used in a various number of diseas...
The design of new photosensitizers with enhanced phototoxicity and pharmacokinetic properties remain...
Pheophorbide a (Pba) is a chlorophyll catabolite that has been proposed as photosensitizer in photod...
Pheophorbide a (Pba) has been pegylated to methoxypolyethylene glycol (mPE G-Pba) to produce a solub...
The design of new photosensitizers with enhanced phototoxicity and pharmacokinetic properties remain...
Pheophorbide a (Pba) is a chlorophyll catabolite that has been proposed as photosensitizer in photod...
Photodynamic therapy (PDT) is an approved but under-development modality for cancer therapy. Convent...
Pheophorbide-a derivatives have been reported to be potential photosensitizers for photodynamic ther...
Abstract Background Photodynamic therapy (PDT) is photo-treatment of malignant or benign diseases us...
Summary Photosensitizers in photodynamic therapy allow for the transfer and trans-lation of light en...
Photodynamic therapy (PDT) is a non-invasive and tumour-specific therapy. Photosensitizers (PSs) (es...
Photodynamic therapy (PDT) utilises light, oxygen and organic macrocycles, called photosensitisers, ...
Abstract: Photodynamic therapy (PDT) was discovered more than 100 years ago, and has since become a ...
Photodynamic therapy (PDT) is based on the use of a photosensitizing agent such as porphyrins, altho...
Photodynamic therapy (PDT) has attracted widespread attention due to its potential in the treatment ...