OBJECTIVE: To determine whether the administration of metformin, an insulin-sensitizing agent, is followed by changes in adrenal steroidogenesis in women with polycystic ovary syndrome (PCOS). DESIGN: Prospective trial. SETTING: Department of Obstetrics and Gynecology, University of Siena, Siena, Italy. PATIENT(S): Fourteen women with PCOS. INTERVENTION(S): Blood samples were obtained before (-15 and 0 minutes) and after (15, 30, 45, and 60 minutes) the administration of ACTH (250 microg). Metformin then was given at a dosage of 500 mg three times a day for 30-32 days, at which time the pretreatment study was repeated. MAIN OUTCOME MEASURE(S): The adrenal androgen responses to ACTH before and after treatment with metformin. RESU...
OBJECTIVE: To investigate metformin effects on the endocrine-metabolic parameters and ovarian morph...
Objective: To evaluate whether pretreatment with metformin improves FSH- induced ovulation in women ...
BACKGROUND: Several data have demonstrated the efficacy of metformin in inducing ovulation in pati...
OBJECTIVE: To determine whether the administration of metformin, an insulin-sensitizing agent, is f...
OBJECTIVE: To investigate the adrenal response in terms of allopregnanolone secretion in a group o...
OBJECTIVE: To evaluate eff ects of metformin on menstrual cyclicity in women with polycystic ovary s...
effects of long-term metformin treatment on adrenal and ovarian steroidogenesis in women with polycy...
Objective(s): To evaluate the effects of metformin on insulin resistance, ovarian androgen productio...
Objective: To investigate the effects of reduction of insulin resistance and hyperinsulinemia associ...
Context: In the adult ovary, antimullerian hormone (AMH) is produced by the granulosa cells of prean...
The aim of study was to evaluate endocrine changes in PCOS women during metformin treatment. One hun...
Background and objectives: Metformin improves manifestations of polycystic ovary syndrome (PCOS) by ...
Objective: To evaluate the effects of metformin administration on spontaneous LH episodic release in...
Background: Objective of the study was to measure the efficacy and safety of insulin sensitizing dru...
Objective: To determine the clinical, hormonal, and biochemical effects of metformin therapy in obes...
OBJECTIVE: To investigate metformin effects on the endocrine-metabolic parameters and ovarian morph...
Objective: To evaluate whether pretreatment with metformin improves FSH- induced ovulation in women ...
BACKGROUND: Several data have demonstrated the efficacy of metformin in inducing ovulation in pati...
OBJECTIVE: To determine whether the administration of metformin, an insulin-sensitizing agent, is f...
OBJECTIVE: To investigate the adrenal response in terms of allopregnanolone secretion in a group o...
OBJECTIVE: To evaluate eff ects of metformin on menstrual cyclicity in women with polycystic ovary s...
effects of long-term metformin treatment on adrenal and ovarian steroidogenesis in women with polycy...
Objective(s): To evaluate the effects of metformin on insulin resistance, ovarian androgen productio...
Objective: To investigate the effects of reduction of insulin resistance and hyperinsulinemia associ...
Context: In the adult ovary, antimullerian hormone (AMH) is produced by the granulosa cells of prean...
The aim of study was to evaluate endocrine changes in PCOS women during metformin treatment. One hun...
Background and objectives: Metformin improves manifestations of polycystic ovary syndrome (PCOS) by ...
Objective: To evaluate the effects of metformin administration on spontaneous LH episodic release in...
Background: Objective of the study was to measure the efficacy and safety of insulin sensitizing dru...
Objective: To determine the clinical, hormonal, and biochemical effects of metformin therapy in obes...
OBJECTIVE: To investigate metformin effects on the endocrine-metabolic parameters and ovarian morph...
Objective: To evaluate whether pretreatment with metformin improves FSH- induced ovulation in women ...
BACKGROUND: Several data have demonstrated the efficacy of metformin in inducing ovulation in pati...