BH3:THF Reduction Reduction of 3-Methylisoxazolo[4,5-c]pyridines

  • Adembri G.
  • Camparini A.
  • Ponticelli F.
  • Tedeschi P.
Publication date
January 1982

Abstract

3-Methylisoxazolo[4,5-c]pyridine 1 on reduction with BH3:THF gave, via the isolable complex 4, the tetrahydroisoxazolopyridine 5. The presence of two chlorine atoms at the 4 and 6 positions directed borane attact to the isoxazole ring, yielding the aminoethylpyridine 8. Both types of reduction were obtained with 6-chloroisoxazolo[4,5-c]pyridine 7. © 1982

Extracted data

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