A substantial proportion of GH circulates bound to high affinity GH-binding protein (GHBP), which corresponds to the extracellular domain of the GH receptor. Current evidence indicates that nutritional status has an important role in regulating plasma GHBP levels in humans. In the present study the relationship among plasma GHBP levels, body composition [by bioelectrical impedance analysis (BIA) and dual energy x-ray absorptiometry (DEXA)] and serum estradiol (E(2)) was evaluated in premenopausal (n = 92) and postmenopausal (n = 118) healthy women with different body weight [three groups according to body mass index (BMI): normal, 18.5-24.99; overweight, 25-29.99; obese, 30-39.99 kg/m(2)]. Plasma GHBP levels were measured by high pressure l...
Context: Dense breast tissue is associated with 4 to 6 times higher risk of breast cancer by poorly ...
This study was performed to evaluate the impact of insulin sensitivity on sex hormone-binding globul...
The aim of the present study was to evaluate the relationship between GHRH-induced GH secretion in o...
A substantial proportion of GH circulates bound to high affinity GH-binding protein (GHBP), which co...
ABSTRACT A substantial proportion of GH circulates bound to high affinity GH-binding protein (GHBP...
The present data indicate a strong direct correlation between GHBP and body fat in premenopausal, bu...
The altered function of the somatotropic axis observed in perimenopause may underlie the changes in ...
Abstract: Objectives: an increasing interest is being focused on the role of the somatotropic axis i...
GH-binding protein (GHBP) corresponds to the extracellular domain of the GH receptor (GHR) and has b...
OBJECTIVES: an increasing interest is being focused on the role of the somatotropic axis in the modu...
Abdominally obese individuals have reduced 24-h plasma GH concentrations. Their normal plasma IGF-I ...
This study was performed to evaluate the impact of insulin sensitivity on sex hormone-binding globul...
The study investigated possible menopause-related changes in circulating insulin-like growth factor ...
Background and Aims: The aim of this study was to determine sex hormone binding globulin (SHBG) conc...
OBJECTIVES: A significant growth hormone (GH) contribution to interindividual variance in energy...
Context: Dense breast tissue is associated with 4 to 6 times higher risk of breast cancer by poorly ...
This study was performed to evaluate the impact of insulin sensitivity on sex hormone-binding globul...
The aim of the present study was to evaluate the relationship between GHRH-induced GH secretion in o...
A substantial proportion of GH circulates bound to high affinity GH-binding protein (GHBP), which co...
ABSTRACT A substantial proportion of GH circulates bound to high affinity GH-binding protein (GHBP...
The present data indicate a strong direct correlation between GHBP and body fat in premenopausal, bu...
The altered function of the somatotropic axis observed in perimenopause may underlie the changes in ...
Abstract: Objectives: an increasing interest is being focused on the role of the somatotropic axis i...
GH-binding protein (GHBP) corresponds to the extracellular domain of the GH receptor (GHR) and has b...
OBJECTIVES: an increasing interest is being focused on the role of the somatotropic axis in the modu...
Abdominally obese individuals have reduced 24-h plasma GH concentrations. Their normal plasma IGF-I ...
This study was performed to evaluate the impact of insulin sensitivity on sex hormone-binding globul...
The study investigated possible menopause-related changes in circulating insulin-like growth factor ...
Background and Aims: The aim of this study was to determine sex hormone binding globulin (SHBG) conc...
OBJECTIVES: A significant growth hormone (GH) contribution to interindividual variance in energy...
Context: Dense breast tissue is associated with 4 to 6 times higher risk of breast cancer by poorly ...
This study was performed to evaluate the impact of insulin sensitivity on sex hormone-binding globul...
The aim of the present study was to evaluate the relationship between GHRH-induced GH secretion in o...