Pyrrole compounds as inibitors of mycobacteria, synthesis thereof and intermediates thereto

Synthesis of pyrrolamide derivates ad intermediate for new antibiotics

Saleh, Ali

December 2016

The obìjectives of the study were to develop a synthetic chemistry route to 4-aminepyrrole-2-carboxy...

1,5-Diphenylpyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings

BIAVA M
PORRETTA G. C
POCE G
DE LOGU A
SADDI M
MELEDDU R
DE ROSSI E
MANETTI, FABRIZIO
BOTTA, MAURIZIO

January 2008

Synthesis and biological evaluation of new derivatives of 1,5-bis(4-chlorophenyl)-2-methyl-3-(4-meth...

1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings

BIAVA M
PORRETTA GC
POCE G
DE LOGU A
SADDI M
MELEDDU R
MANETTI F
DE ROSSI E
BOTTA M

January 2008

Synthesis and biological evaluation of new derivatives of 1,5-bis(4-chlorophenyl)-2-methyl-3-(4-meth...

Pyrrole compounds as inibitors of mycobacteria, synthesis thereof and intermediates thereto

M. BIAVA
F. MANETTI
R. POMPEI
A. DE LOGU
M. BOTTA
G. C. PORRETTA

January 2012

The present invention relates to a compound having the general formula (3): synthesis, intermediates...

Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto

Biava M
Porretta GC
Pompei R
De Logu A.
BOTTA, MAURIZIO
MANETTI, FABRIZIO

January 2013

The present invention concerns novel pyrrole compounds, derivatives of 1-{[1,5-bis(4-chlorophenyl)-2...

Antimycobacterial compounds. New pyrrole derivatives of BM212

BIAVA M.
PORRETTA G. C.
DEIDDA D.
POMPEI R.
TAFI, ANDREA
MANETTI, FABRIZIO

January 2004

We have identified BM212 as a lead compound among a series of pyrrole derivatives with good in vitro...

Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class

Mariangela Biava
Giulio Cesare Porretta
Giovanna Poce
Delia Deidda
Raffaello Pompei
Andrea Tafi
Fabrizio Manetti

January 2005

Our work on antitubercular agents led to the identification of BM 212 as a lead compound among a ser...

Antimycobacterial compounds. Optimization of the BM212 structure, the lead compound for a new pyrrole derivative class

Biava, M
Porretta, Gc
Poce, G
Deidda, D
Pompei, R
Tafi, Andrea
Manetti, Fabrizio

January 2005

Our work on antitubercular agents led to the identification of BM 212 as a lead compound among a ser...

New derivatives of BM212. a class of antimycobacterial compounds based on the pyrrole ring as a scaffold

BIAVA M
PORRETTA G. C
MANETTI, FABRIZIO

January 2007

During our investigation in the area of antimycobacterial agents, we have identified the 1,5-(4-chlo...

1,5-Diphenyl Pyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings

BIAVA M
PORRETTA GC
G. POCE
DE LOGU A
SADDI M
MELEDDU R
MANETTI F
DE ROSSI E
BOTTA M

January 2008

Synthesis and biological evaluation of new derivatives of 1,5-bis(4-chlorophenyl)-2-methyl-3-(4-meth...

Derivatives of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine, synthesis process and uses thereof

BOTTA, MAURIZIO
MANETTI, FABRIZIO
R. POMPEI
M. BIAVA
D. DEIDDA
G. C. PORRETTA

January 2006

The present invention concerns pyrrole compounds, derivatives of 1-([1,5-bis(4-chlorophenyl)-2-methy...

Importance of the Thiomorpholine Introduction in New Pyrrole Derivatives as Antimycobacterial Agents Analogues of BM 212

MANETTI, FABRIZIO
TAFI, ANDREA
R. POMPEI
M. BIAVA
D. DEIDDA
G. C. PORRETTA

January 2003

During the course of our investigations in the field of azole antimicrobial agents, we have identifi...

Synthesis of pyrrolamide derivates ad intermediate for new antibiotics

Saleh, Ali

December 2016

The obìjectives of the study were to develop a synthetic chemistry route to 4-aminepyrrole-2-carboxy...

1,5-Diphenylpyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings

BIAVA M
PORRETTA G. C
POCE G
DE LOGU A
SADDI M
MELEDDU R
DE ROSSI E
MANETTI, FABRIZIO
BOTTA, MAURIZIO

January 2008

Synthesis and biological evaluation of new derivatives of 1,5-bis(4-chlorophenyl)-2-methyl-3-(4-meth...

1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings

BIAVA M
PORRETTA GC
POCE G
DE LOGU A
SADDI M
MELEDDU R
MANETTI F
DE ROSSI E
BOTTA M

January 2008

Synthesis and biological evaluation of new derivatives of 1,5-bis(4-chlorophenyl)-2-methyl-3-(4-meth...

Pyrrole compounds as inibitors of mycobacteria, synthesis thereof and intermediates thereto

M. BIAVA
F. MANETTI
R. POMPEI
A. DE LOGU
M. BOTTA
G. C. PORRETTA

January 2012

The present invention relates to a compound having the general formula (3): synthesis, intermediates...

Pyrrole compounds as inhibitors of mycobacteria, synthesis thereof ans intermediates thereto

Biava M
Porretta GC
Pompei R
De Logu A.
BOTTA, MAURIZIO
MANETTI, FABRIZIO

January 2013

The present invention concerns novel pyrrole compounds, derivatives of 1-{[1,5-bis(4-chlorophenyl)-2...

Antimycobacterial compounds. New pyrrole derivatives of BM212

BIAVA M.
PORRETTA G. C.
DEIDDA D.
POMPEI R.
TAFI, ANDREA
MANETTI, FABRIZIO

January 2004

We have identified BM212 as a lead compound among a series of pyrrole derivatives with good in vitro...

Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class

Mariangela Biava
Giulio Cesare Porretta
Giovanna Poce
Delia Deidda
Raffaello Pompei
Andrea Tafi
Fabrizio Manetti

January 2005

Our work on antitubercular agents led to the identification of BM 212 as a lead compound among a ser...

Antimycobacterial compounds. Optimization of the BM212 structure, the lead compound for a new pyrrole derivative class

Biava, M
Porretta, Gc
Poce, G
Deidda, D
Pompei, R
Tafi, Andrea
Manetti, Fabrizio

January 2005

Our work on antitubercular agents led to the identification of BM 212 as a lead compound among a ser...

New derivatives of BM212. a class of antimycobacterial compounds based on the pyrrole ring as a scaffold

BIAVA M
PORRETTA G. C
MANETTI, FABRIZIO

January 2007

During our investigation in the area of antimycobacterial agents, we have identified the 1,5-(4-chlo...

1,5-Diphenyl Pyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings

BIAVA M
PORRETTA GC
G. POCE
DE LOGU A
SADDI M
MELEDDU R
MANETTI F
DE ROSSI E
BOTTA M

January 2008

Synthesis and biological evaluation of new derivatives of 1,5-bis(4-chlorophenyl)-2-methyl-3-(4-meth...

Derivatives of 1-{[1,5-bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl]methyl}-4-methylpiperazine, synthesis process and uses thereof

BOTTA, MAURIZIO
MANETTI, FABRIZIO
R. POMPEI
M. BIAVA
D. DEIDDA
G. C. PORRETTA

January 2006

The present invention concerns pyrrole compounds, derivatives of 1-([1,5-bis(4-chlorophenyl)-2-methy...

Importance of the Thiomorpholine Introduction in New Pyrrole Derivatives as Antimycobacterial Agents Analogues of BM 212

MANETTI, FABRIZIO
TAFI, ANDREA
R. POMPEI
M. BIAVA
D. DEIDDA
G. C. PORRETTA

January 2003

During the course of our investigations in the field of azole antimicrobial agents, we have identifi...

Synthesis of pyrrolamide derivates ad intermediate for new antibiotics

Saleh, Ali

December 2016

The obìjectives of the study were to develop a synthetic chemistry route to 4-aminepyrrole-2-carboxy...

1,5-Diphenylpyrrole Derivatives as Antimycobacterial Agents. Probing the Influence on Antimycobacterial Activity of Lipophilic Substituents at the Phenyl Rings

BIAVA M
PORRETTA G. C
POCE G
DE LOGU A
SADDI M
MELEDDU R
DE ROSSI E
MANETTI, FABRIZIO
BOTTA, MAURIZIO

January 2008

Synthesis and biological evaluation of new derivatives of 1,5-bis(4-chlorophenyl)-2-methyl-3-(4-meth...

1,5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings

BIAVA M
PORRETTA GC
POCE G
DE LOGU A
SADDI M
MELEDDU R
MANETTI F
DE ROSSI E
BOTTA M

January 2008

Synthesis and biological evaluation of new derivatives of 1,5-bis(4-chlorophenyl)-2-methyl-3-(4-meth...

Pyrrole compounds as inibitors of mycobacteria, synthesis thereof and intermediates thereto

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Pyrrole compounds as inibitors of mycobacteria, synthesis thereof and intermediates thereto

Abstract

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