Background: Risk stratification in patients with papillary thyroid carcinoma (PTC) currently relies on postoperative parameters. Testing for BRAF mutations preoperatively may serve as a novel tool for identifying PTC patients at risk of persistence/recurrence after surgery. Methods: The study involved 185 consecutive patients with a histological diagnosis of PTC and BRAF analysis performed on thyroid fine-needle aspiration biopsy (FNAB). We assessed BRAF status in FNAB specimens obtained before thyroidectomy for PTC, and examined its association with the clinicopathological characteristics identified postoperatively, and with outcome after a mean 55\ub115 months of follow-up. Results: One hundred and fifteen of 185 (62%) PTCs carried a BR...
Background-Aim: The use of preoperative lymphoscintigraphy and intraoperative gamma probe detection ...
PURPOSE: To investigate the prognostic value of BRAF V600E mutation for the recurrence of papill...
OBJECTIVE: Preoperative fine needle aspiration biopsy (FNAB) has become the initial diagnostic metho...
The mutation BRAF V600E is thought to be a putative prognostic marker of the aggressiveness of sever...
Background: The BRAF mutation has been shown to be associated with aggressive clinicopathologic char...
Background: BRAF mutation is probably the only molecular marker acting as a risk factor that is avai...
Background: The current preoperative diagnosis of a thyroid mass relies on microscopic evaluation of...
SummaryObjectivesBRAF pV600E mutation is the most common oncogenic event and the most specific mutat...
<p>Background</p><p>Papillary thyroid microcarcinoma (PTMC) is heterogeneous group of tumor less tha...
BACKGROUND: To evaluate the relationship between the BRAF V600E mutation and clinicopathologic param...
BACKGROUND: The association between the BRAF mutation and persistence/recurrence was investigated in...
Abstract CONTEXT: Because very few studies have examined the correlation between BRAF mutations an...
BACKGROUND: BRAF(V600E) mutation, which represents the most frequent genetic mutation in papillary t...
Context: Because very few studies have examined the correlation between BRAF mutations and clinicopa...
Background: The BRAF(V600E) mutation is the most frequent genetic alteration in papillary thyroid ca...
Background-Aim: The use of preoperative lymphoscintigraphy and intraoperative gamma probe detection ...
PURPOSE: To investigate the prognostic value of BRAF V600E mutation for the recurrence of papill...
OBJECTIVE: Preoperative fine needle aspiration biopsy (FNAB) has become the initial diagnostic metho...
The mutation BRAF V600E is thought to be a putative prognostic marker of the aggressiveness of sever...
Background: The BRAF mutation has been shown to be associated with aggressive clinicopathologic char...
Background: BRAF mutation is probably the only molecular marker acting as a risk factor that is avai...
Background: The current preoperative diagnosis of a thyroid mass relies on microscopic evaluation of...
SummaryObjectivesBRAF pV600E mutation is the most common oncogenic event and the most specific mutat...
<p>Background</p><p>Papillary thyroid microcarcinoma (PTMC) is heterogeneous group of tumor less tha...
BACKGROUND: To evaluate the relationship between the BRAF V600E mutation and clinicopathologic param...
BACKGROUND: The association between the BRAF mutation and persistence/recurrence was investigated in...
Abstract CONTEXT: Because very few studies have examined the correlation between BRAF mutations an...
BACKGROUND: BRAF(V600E) mutation, which represents the most frequent genetic mutation in papillary t...
Context: Because very few studies have examined the correlation between BRAF mutations and clinicopa...
Background: The BRAF(V600E) mutation is the most frequent genetic alteration in papillary thyroid ca...
Background-Aim: The use of preoperative lymphoscintigraphy and intraoperative gamma probe detection ...
PURPOSE: To investigate the prognostic value of BRAF V600E mutation for the recurrence of papill...
OBJECTIVE: Preoperative fine needle aspiration biopsy (FNAB) has become the initial diagnostic metho...