D-dimer levels and 90-day outcome in patients with acute pulmonary embolism with or without cancer
- Ana, Maestre
- Javier Trujillo, Santos
- Adriana, Vison\ue1
- Jos\ue9 Lu\ueds, Lobo
- Enric, Grau
- Radovan, Mal\ufd
- Rita, Duce
- Manuel, Monreal
- Alcalde, M
- Arcelus, Ji
- Ballaz, A
- Barba, R
- Barr\uf3n, M
- Barr\uf3n Andr\ue9s, B
- Bascu\uf1ana, J
- Bedate, P
- Blanco Molina, A
- Bueso, T
- Casado, I
- Conget, F
- del Molino, F
- del Toro, J
- Falg\ue1, C
- Fern\ue1ndez Capit\ue1n, C
- Fuentes, Mi
- Gallego, P
- Garc\ueda, J
- Garc\ueda Bragado, F
- Gav\uedn, O
- G\uf3mez, V
- Gonz\ue1lez, J
- Gonz\ue1lez Bachs, E
- Grau, E
- Guil, M
- Guijarro, R
- Guti\ue9rrez, J
- Hern\ue1ndez, L
- Jara Palomares, L
- Jaras, Mj
- Jim\ue9nez, D
- Jim\ue9nez, S
- Lobo, Jl
- L\uf3pez Jim\ue9nez, L
- L\uf3pez S\ue1ez, Jb
- Lorente, Ma
- Lorenzo, A
- Luque, Jm
- Madridano, O
- Maci\ue0, M
- Maestre, A
- Marchena, Pj
- Mart\uedn, M
- Monreal, M
- Mora, Jm
- Mu\uf1oz, Fj
- Nauffal, Md
- Nieto, Ja
- N\ufa\uf1ez, Mj
- Ogea, Jl
- Otero, R
- Pedrajas, Jm
- Peris, Ml
- Riera Mestre, A
- Rivas, A
- Rodr\uedguez D\ue1vila, Ma
- Rom\ue1n, P
- Rosa, V
- Ruiz, J
- Ruiz Rib\uf3, Md
- Ruiz Gamietea, A
- Ruiz Gim\ue9nez, N
- Sahuquillo, Jc
- Samperiz, A
- S\ue1nchez Mu\uf1oz Torrero, Jf
- Soler, S
- Tiberio, G
- Tilvan, Rm
- Tolosa, C
- Trujillo, J
- Uresandi, F
- Vald\ue9s, M
- Valero, B
- Valle, R
- Vela, J
- Vidal, G
- Villalobos, A
- Villalta, J
- Mal\ufd, R
- Hirmerova, J
- Tomko, T
- Bertoletti, L
- Bura Riviere, A
- Farge Bancel, D
- Grange, C
- Hij, A
- Mahe, I
- Merah, A
- Quere, I
- Schellong, S
- Babalis, D
- Papadakis, M
- Tzinieris, I
- Braester, A
- Brenner, B
- Tzoran, I
- Zeltser, D
- Barillari, G
- Ciammaichella, M
- Dalla Valle, F
- Di Micco, P
- Duce, R
- Maida, R
- Pasca, S
- Piovella, C
- Poggio, R
- Prandoni, Paolo
- Quintavalla, R
- Rocci, A
- Rota, L
- Schenone, A
- Tiraferri, E
- Tonello, D
- Tufano, A
- Vison\ue0, A
- Zalunardo, B
- Brinquinho, M
- Gomes, D
- Gon\ue7alves, F
- Santos, M
- Saraiva, M
- Bosevski, M
- Kovacevic, D
- Alatri, A
- Aujeski, D
- Bounameaux, H
- Calanca, L
- Mazzolai, L.
DOIAbstract
BACKGROUND: The prognostic value of D-dimer testing in patients with acute pulmonary embolism (PE) has not been thoroughly studied. METHODS: We used the RIETE Registry data to assess the 90-day prognostic value of increased IL Test D-dimer levels at baseline in patients with PE, according to the presence or absence of cancer. RESULTS: As of May 2013, 3,283 patients with acute PE underwent D-dimer testing using IL Test D-dimer. Among 2,588 patients without cancer, those with D-dimer levels in the highest quartile had a higher rate of fatal PE (2.6% vs. 0.9%; p=0.002), fatal bleeding (1.1% vs. 0.3%; p=0.017) and all-cause death (9.1% vs. 4.4%; p<0.001) at 90 days compared with those with levels in the lowest quartiles. Among 695 patie...
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