Spectral Analysis of the Laser Doppler Perfusion Signal in Patients with Critical Limb Ischemia after Limb Revascularization

In 19 patients with critical limb ischemia the skin flowmotion was studied with spectral wavelet analysis (WA of the laser Doppler signals (LDS)). The LDS was measured at the foot dorsum, one week before and no later than 30 days after revascularization. The aim was to investigate which of the six frequency components (FCs) selected with WA; FC I 1-2 Hz cardiac, FC II 0.2 Hz respiratory-systemic sympathetic nervous, FC III 0.1 Hz myogenic, FC IV 0.04 Hz, local-sympathetic, FC V 0.01 Hz, and FC VI 0.007 Hz endothelial, changed after revascularization. Only in patients with direct revascularization of the foot arteries there was a statistic increase of FC I absolute amplitude and energy from 0.64\ub1 0.4 to 1.21\ub10.72 (P < 0.002) AU and 1.39\ub11.97 to 4.52\ub14.20 AU2 (P < 0.01) and the absolute amplitude of FC III increased from 1.35\ub1 0.51 to 2.86 \ub12.20 AU (P < 0.04