Determination of quality and safety of dietary supplements using separation techniques

Dodaci prehrani izvor su hranjivih tvari poput vitamina, minerala i biljnih ekstrakata, te se koriste kao nadopuna prehrani ako se hranjive tvari nedovoljno unose putem hrane. Posljednjih godina trend proizvodnje i konzumacije dodataka prehrani raste te danas postoji širok asortiman proizvoda. Mnogi proizvodi osim obogaćivanja prehrane hranjivim tvarima navode i djelotvorne učinke poput smanjenja apetita, povećanja mišićne mase i slično. Da bi se postigli djelotvorni učinci osim dozvoljenih sastojaka dodacima prehrani dodaju se sintetski proizvedene tvari i farmaceutici koji su inače sastavni dio lijekova, to dovodi u pitanje kvalitetu i sigurnost dodataka prehrani, a time i potrebu za razvijanjem novih analitičkih metoda analize. U ovom radu opisane su i objašnjene separacijske metode koje se koriste za analizu dodataka prehrani. Opisani su principi analiza i primjena metoda kod analiza dodataka prehrani.Dietary supplements are a source of nutrients such as vitamins, minerals and plant extracts. They are used as a supplement in diet if nutrients are insufficiently ingested through the food. Dietary supplement production and use has increased over recent years, therefore today there is a wide range of products. Many products, in addition to enriching the diet with nutrients, also have a positive effect on reducing appetite, building muscle mass, etc. In addition to the permitted ingredients, components of medications such as synthetic substances and pharmaceuticals, are added to food supplements, this calls into question the quality and safety of dietary supplements, and hence the need for analytical methods of analysis. This thesis describes and explains the separation methods used for the analysis of dietary supplements as well as the principles of analysis and application of methods in the analysis of dietary supplements