ANALYSIS OF THE TREATMENT OF SARS-COV-2 POSITIVE PATIENTS IN CLINICAL HOSPITAL CENTRE RIJEKA IN A TWO-YEAR PERIOD

U ovoj retrospektivnoj kohortnoj studiji analizirani su podaci 910 bolesnika oboljelih od COVID-19 i primljenih u Respiracijski centar KBC-a Rijeka u razdoblju od 28. ožujka 2020. do 28. ožujka 2022. Podatci su dobiveni uvidom u podatke bolesnika pomoću integriranog bolničkog informacijskog sustava (IBIS) te knjiga protokola CRC-a. Sakupljeni podatci obrađeni su korištenjem programa STATISTICA 14.0.0.15 (StatSoft, Inc., Tulsa, OK, SAD) i Excel 2019 (MSFT, Redmond, WA, Sjedinjene Američke Države). Rad je analizirao osnovne podatke poput spola i dobi, trajanje boravka na odjelu u danima, trajanje primjene strojne ventilacije, neinvazivne ventilacije te „high-flow“ nosne kanile u satima, ishod liječenja bolesnika, komorbiditeti bolesnika prije hospitalizacije na CRC-u. Analiza je pokazala da je većina bolesnika bila je u dobnoj skupini od 60 do 70 godina. Omjer muškaraca i žena bio je 2 : 1. Od svih bolesnika više od 60% imalo je neki od komorbiditeta. Šećerna bolest, kronične bolesti dišnog sustava, hipertenzija, kardiovaskularne bolesti, kronična bolest bubrega i karcinom bili su najčešći komorbiditeti. Rezultati ove studije pokazali su da su muški spol, starija dob, kronična bubrežna bolest, kardiovaskularni komorbiditeti, šećerna bolest i arterijska hipertenzija bili su značajno povezani sa smrtnošću među oboljelima na intenzivnom liječenju od COVID-19. Stoga je tijekom epidemije posebno važno obratiti pozornost na muške starije bolesnike sa šećernom bolešću, hipertenzijom, kardiovaskularnim bolestima i kroničnom bolesti bubrega.This retrospective cohort study analysed data from 910 hospitalisations of patients with COVID-19 who were admitted to the COVID19 Respiratory Centre (CRC) of KBC Rijeka in the period from March 28th, 2020 to March 28th, 2022. Data was obtained by reviewing patient data using the Integrated Hospital Information System (IBIS) and from written records of the CRC. The collected data was analysed using the programs STATISTICA 4.0.0.15 (StatSoft, Inc., Tulsa, OK, SAD) and Excel 2019 (MSFT, Redmond, WA, SAD). Examined patient characteristics included age, sex, the length of stay in days, the length of mechanical ventilation support, the outcome of the treatment, and underlying disease before the hospitalisation. The analysis has shown that most of the cases were in the group of 60 to 70 years of age. The male to female ratio was 2: 1. Out of all analysed patients, more than 60%, had at least one comorbidity. Diabetes, chronic respiratory disease, hypertension, cardiovascular disease, chronic kidney disease, and cancer were the most common comorbidities. Male gender, old age, and comorbidities were significantly associated with increased mortality. The results of this study, in fact, highlighted male gender, older age, diabetes, hypertension, chronic kidney disease and cardiovascular comorbidities as significantly associated with the risk of death among COVID-19 patients in the intensive care. Therefore, during the epidemic it is especially important to pay attention to male elderly patients with diabetes mellitus, hypertension, cardiovascular disease and chronic kidney disease