Add to ORKGPrimary Sjögren's syndrome (pSS) is a chronic autoimmune disorder affecting exocrine glands of the body, prevalently lacrimal and salivary glands. The pSS pathogenesis has been thought to be B-cell-centric and several clinical trials have been carried out in order to clarify the therapeutic role of B-cell depletion in patients with pSS. Unfortunately, however, B-cell depletion with rituximab has failed in demonstrating any significant results in pSS patients. Besides the contribution of B cells in the pathogenesis of pSS, effector Tfh, Th17 and Th22 cells, follicular dendritic cells (DCs), innate cells (ICs) and several cytokines, chemokines and miRNA have been proved to participate to the development of this systemic disease. Understanding...
A histologic hallmark of primary SS (pSS) is lymphocytic infiltration of the salivary and lacrimal g...
ABSTRACTPrimary Sjögren syndrome (pSjS) is an autoimmune disease, in which a large number of lymphoc...
International audienceObjectives: Primary Sjögren's syndrome (pSS) is characterized by chronic hyper...
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder affecting exocrine glands of the b...
International audiencePrimary Sjögren's syndrome (pSS) is a chronic autoimmune systemic disease, cha...
In vitro and in vivo experimental data have pointed to new immunopathogenic mechanisms in primary Sj...
Primary Sjögren's syndrome (pSS) is an autoimmune exocrinopathy characterized by chronic inflammatio...
Primary Sjögren's syndrome (pSS) is often considered a B cell-mediated disease, yet the precise role...
Primary Sjögren's syndrome (pSS) is a chronic inflammatory autoimmune disease, characterised by a ch...
The pathogenesis of primary Sjögren's (pSS) remains an area of intense research. A triggering factor...
Primary Sjogren Syndrome (pSS) is a complex, multifactorial rheumatic disease that mainly targets sa...
International audienceBiological abnormalities associated with B lymphocytes are a hallmark of patie...
There are many studies done to determine factors what can cause susceptibility to Sjögren's syndrome...
Primary Sjögren's syndrome (pSS) is characterized by mononuclear inflammatory infiltrates and IgG pl...
A histologic hallmark of primary SS (pSS) is lymphocytic infiltration of the salivary and lacrimal g...
ABSTRACTPrimary Sjögren syndrome (pSjS) is an autoimmune disease, in which a large number of lymphoc...
International audienceObjectives: Primary Sjögren's syndrome (pSS) is characterized by chronic hyper...
Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder affecting exocrine glands of the b...
International audiencePrimary Sjögren's syndrome (pSS) is a chronic autoimmune systemic disease, cha...
In vitro and in vivo experimental data have pointed to new immunopathogenic mechanisms in primary Sj...
Primary Sjögren's syndrome (pSS) is an autoimmune exocrinopathy characterized by chronic inflammatio...
Primary Sjögren's syndrome (pSS) is often considered a B cell-mediated disease, yet the precise role...
Primary Sjögren's syndrome (pSS) is a chronic inflammatory autoimmune disease, characterised by a ch...
The pathogenesis of primary Sjögren's (pSS) remains an area of intense research. A triggering factor...
Primary Sjogren Syndrome (pSS) is a complex, multifactorial rheumatic disease that mainly targets sa...
International audienceBiological abnormalities associated with B lymphocytes are a hallmark of patie...
There are many studies done to determine factors what can cause susceptibility to Sjögren's syndrome...
Primary Sjögren's syndrome (pSS) is characterized by mononuclear inflammatory infiltrates and IgG pl...
A histologic hallmark of primary SS (pSS) is lymphocytic infiltration of the salivary and lacrimal g...
ABSTRACTPrimary Sjögren syndrome (pSjS) is an autoimmune disease, in which a large number of lymphoc...
International audienceObjectives: Primary Sjögren's syndrome (pSS) is characterized by chronic hyper...