Literature review on the cross-link between ocular and renal disease: renin angiotensin aldosterone system is a main actor
- Lai S.
- Perrotta A. M.
- Bagordo D.
- Mazzaferro S.
- Mene P.
- Errigo F.
- Tinti F.
- Rotondi S.
- Molfino A.
- Simeoni M.
- Mitterhofer A. P.
- Cianci R.
DOIAbstract
Chronic kidney disease (CKD) and ocular disease share several cardiovascular risk factors as well as pathogenetic mechanisms having Renin-Angiotensin-Aldosterone System (RAAS) as main actor. Moreover, kidney and eyes have common genetic and embryonic origin. In this literature review, we present main evidence supporting this association for early identifying diseases affecting both systems and evaluating potential multi-target therapeutic strategies
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