The overall diagnostic yield of massively parallel sequencing-based tests in patients with chronic kidney disease (CKD) is 30% for paediatric cases and 6-30% for adult cases. These figures should encourage nephrologists to frequently use genetic testing as a diagnostic means for their patients. However, in reality, several barriers appear to hinder the implementation of massively parallel sequencing-based diagnostics in routine clinical practice. In this article we aim to support the nephrologist to overcome these barriers. After a detailed discussion of the general items that are important to genetic testing in nephrology, namely genetic testing modalities and their indications, clinical information needed for high-quality interpretation o...
Advances in next-generation sequencing (NGS) techniques, including whole exome sequencing, have faci...
Inherited kidney diseases (IKDs) are among the leading causes of early-onset chronic kidney disease ...
INTRODUCTION: Chronic kidney disease (CKD) can be caused by a variety of systemic or primary renal d...
The overall diagnostic yield of massively parallel sequencing-based tests in patients with chronic k...
The overall diagnostic yield of massively parallel sequencing (MPS) based-tests in patients with chr...
The overall diagnostic yield of massively parallel sequencing-based tests in patients with chronic k...
The overall diagnostic yield of massively parallel sequencing-based tests in patients with chronic k...
Genetic kidney disease comprises a diverse group of disorders. These can roughly be divided in the p...
Chronic kidney disease (CKD) is considered a major global health problem with high socio-economic co...
Numerous genes for monogenic kidney diseases with classical patterns of inheritance, as well as gene...
Key differences exist between clinical and research genomics. As genomic testing is adopted in nephr...
Advances in next-generation sequencing (NGS) techniques, including whole exome sequencing, have faci...
Inherited kidney diseases (IKDs) are among the leading causes of early-onset chronic kidney disease ...
INTRODUCTION: Chronic kidney disease (CKD) can be caused by a variety of systemic or primary renal d...
The overall diagnostic yield of massively parallel sequencing-based tests in patients with chronic k...
The overall diagnostic yield of massively parallel sequencing (MPS) based-tests in patients with chr...
The overall diagnostic yield of massively parallel sequencing-based tests in patients with chronic k...
The overall diagnostic yield of massively parallel sequencing-based tests in patients with chronic k...
Genetic kidney disease comprises a diverse group of disorders. These can roughly be divided in the p...
Chronic kidney disease (CKD) is considered a major global health problem with high socio-economic co...
Numerous genes for monogenic kidney diseases with classical patterns of inheritance, as well as gene...
Key differences exist between clinical and research genomics. As genomic testing is adopted in nephr...
Advances in next-generation sequencing (NGS) techniques, including whole exome sequencing, have faci...
Inherited kidney diseases (IKDs) are among the leading causes of early-onset chronic kidney disease ...
INTRODUCTION: Chronic kidney disease (CKD) can be caused by a variety of systemic or primary renal d...