Add to ORKGSimilarly to other serotypes, botulinum neurotoxin serotype G (BoNT/G) contains the zinc binding motif of zinc endopeptidases. Highly purified preparations of BoNT/G show a zinc-dependent protease activity specific for VAMP/synaptobrevin, a membrane protein of synaptic vesicles. The two neuronal VAMP isoforms are cleaved with similar rates at one Ala-Ala peptide bond present in the same region, out of the several such peptide bonds present in their sequences. This site of cleavage is unique among the eight clostridial neurotoxins. VAMP proteolysis is displayed only after reduction of the single interchain disulfide bond present in the toxin, and it is inhibited by EDTA, o-phenanthroline and captopri
AbstractBotulinum neurotoxins (BoNTs) cause botulism by cleaving proteins necessary for nerve transm...
Botulinum Neurotoxins (BoNTs) are the causative agents of botulism, which act by potently inhibiting...
The botulinum neurotoxins (BoNT, serotypes A-G) are some of the most toxic proteins known and are th...
Similarly to other serotypes, botulinum neurotoxin serotype G (BoNT/G) contains the zinc binding mot...
Similarly to other serotypes, botulinum neurotoxin serotype G (BoNT/G) contains the zinc binding mot...
Botulinum neurotoxin serotype F contains the zinc binding motif of zinc endopeptidases. Atomic adsor...
Botulinum neurotoxins are metalloproteins with one zinc atom bound to the zinc binding motif of zinc...
Botulinum neurotoxins (BoNTs) are among the most potent toxins known and are also used to treat an i...
AbstractBotulinum neurotoxins type D and F are zinc-endopeptidases with a unique specificity for VAM...
Botulinum neurotoxins are known to have seven serotypes (BoNT/A–G). Here we report a new BoNT seroty...
Tetanus and botulinum neurotoxins type B and G are zinc-endopeptidases of remarkable specificity. Th...
Botulinum neurotoxins (BoNT) are produced by several species of clostridium. There are seven immunol...
International audienceBotulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) inhibit neurotrans...
Tetanus toxin (TeTx) and the various forms of botulinal neurotoxins (BoNT/A to BoNT/G) potently inhi...
Botulinum neurotoxins types B, D, F, and G, and tetanus neurotoxin inhibit vesicular fusion via prot...
AbstractBotulinum neurotoxins (BoNTs) cause botulism by cleaving proteins necessary for nerve transm...
Botulinum Neurotoxins (BoNTs) are the causative agents of botulism, which act by potently inhibiting...
The botulinum neurotoxins (BoNT, serotypes A-G) are some of the most toxic proteins known and are th...
Similarly to other serotypes, botulinum neurotoxin serotype G (BoNT/G) contains the zinc binding mot...
Similarly to other serotypes, botulinum neurotoxin serotype G (BoNT/G) contains the zinc binding mot...
Botulinum neurotoxin serotype F contains the zinc binding motif of zinc endopeptidases. Atomic adsor...
Botulinum neurotoxins are metalloproteins with one zinc atom bound to the zinc binding motif of zinc...
Botulinum neurotoxins (BoNTs) are among the most potent toxins known and are also used to treat an i...
AbstractBotulinum neurotoxins type D and F are zinc-endopeptidases with a unique specificity for VAM...
Botulinum neurotoxins are known to have seven serotypes (BoNT/A–G). Here we report a new BoNT seroty...
Tetanus and botulinum neurotoxins type B and G are zinc-endopeptidases of remarkable specificity. Th...
Botulinum neurotoxins (BoNT) are produced by several species of clostridium. There are seven immunol...
International audienceBotulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) inhibit neurotrans...
Tetanus toxin (TeTx) and the various forms of botulinal neurotoxins (BoNT/A to BoNT/G) potently inhi...
Botulinum neurotoxins types B, D, F, and G, and tetanus neurotoxin inhibit vesicular fusion via prot...
AbstractBotulinum neurotoxins (BoNTs) cause botulism by cleaving proteins necessary for nerve transm...
Botulinum Neurotoxins (BoNTs) are the causative agents of botulism, which act by potently inhibiting...
The botulinum neurotoxins (BoNT, serotypes A-G) are some of the most toxic proteins known and are th...