The principal neutralizing domain (PND) of HIV-1, located within the third variable region (V3) of the gp120 envelope protein, is related to the humoral and cellular immune response. We studied the V3 PND-specific antibody response in 30 children with vertically acquired HIV-1 infection by determining the antibodies that bound synthetic peptides derived from the PND of the HIV-1MN, HIV-1SF-2, HIV-1SC, HIV-1IIIB, HIV-1RF, HIV-1ELI, and HIV-1Z6 virus strains. At a standard antigen concentration, we found that most sera (90%) reacted against PND(MN) Peptide, but 73.3 % also cross-reacted against multiple PNDs. A search for high-affinity/avidity antibodies was conducted in an antigen-limited assay; at lower peptide concentrations, cross-reactiv...
Various seroepidemiological studies have detected a 22-39% risk of maternal-child transmission of th...
Background: Neutralization sensitivity of HIV-1 virus to antibodies and anti-sera varies greatly bet...
Neutralization sensitivity of HIV-1 virus to antibodies and anti-sera varies greatly between the iso...
The principal neutralizing domain (PND) of HIV-1, located within the third variable region (V3) of t...
Production of cross-reactive antibodies recognizing the V3 loop--that is, the principal neutralizing...
The V3 loop of the HIV-1 envelope (Env) glycoprotein gp120 was identified as the “principal neutrali...
The V3 loop of the HIV-1 envelope (Env) glycoprotein gp120 was identified as the "principal neutrali...
AbstractThe HIV-1 gp120 V3 loop is a potent inducer of neutralizing antibodies for T cell line adapt...
Human immunodeficiency virus type 1 serotype C was found in 545 of 712 Ethiopian patients by peptide...
The third variable region (V3) of the envelope protein of human immunodeficiency virus type 1 (HIV-1...
We have analyzed a panel of eight murine monoclonal antibodies (MAbs) that depend on the V2 domain f...
We analysed HIV-specific immunoglobulin G (IgG) responses to gag and env peptides in infants born to...
The early autologous neutralizing antibody response in human immunodeficiency virus type 1 (HIV-1) s...
textabstractA type-specific human immunodeficiency virus type 1 (HIV-1)-neutralizing human monoclona...
Previous studies have demonstrated a stronger seroreactivity against some synthetic peptides respons...
Various seroepidemiological studies have detected a 22-39% risk of maternal-child transmission of th...
Background: Neutralization sensitivity of HIV-1 virus to antibodies and anti-sera varies greatly bet...
Neutralization sensitivity of HIV-1 virus to antibodies and anti-sera varies greatly between the iso...
The principal neutralizing domain (PND) of HIV-1, located within the third variable region (V3) of t...
Production of cross-reactive antibodies recognizing the V3 loop--that is, the principal neutralizing...
The V3 loop of the HIV-1 envelope (Env) glycoprotein gp120 was identified as the “principal neutrali...
The V3 loop of the HIV-1 envelope (Env) glycoprotein gp120 was identified as the "principal neutrali...
AbstractThe HIV-1 gp120 V3 loop is a potent inducer of neutralizing antibodies for T cell line adapt...
Human immunodeficiency virus type 1 serotype C was found in 545 of 712 Ethiopian patients by peptide...
The third variable region (V3) of the envelope protein of human immunodeficiency virus type 1 (HIV-1...
We have analyzed a panel of eight murine monoclonal antibodies (MAbs) that depend on the V2 domain f...
We analysed HIV-specific immunoglobulin G (IgG) responses to gag and env peptides in infants born to...
The early autologous neutralizing antibody response in human immunodeficiency virus type 1 (HIV-1) s...
textabstractA type-specific human immunodeficiency virus type 1 (HIV-1)-neutralizing human monoclona...
Previous studies have demonstrated a stronger seroreactivity against some synthetic peptides respons...
Various seroepidemiological studies have detected a 22-39% risk of maternal-child transmission of th...
Background: Neutralization sensitivity of HIV-1 virus to antibodies and anti-sera varies greatly bet...
Neutralization sensitivity of HIV-1 virus to antibodies and anti-sera varies greatly between the iso...