A Platform For Liposomal Drug Delivery

Liposome has been used as a carrier to transport a wide variety of compounds in its aqueous compartment. The clinicalpotential of liposomes as a vehicle for replacement therapy in genetic deficiencies of lysosomal enzymes was firstestablished in 1970. Liposomes are surfactants, sphingolipids, glycolipids, long chain fatty acids and even membraneproteins and drug molecules or it is also called vesicular system. These are different in size, composition and charge. Theseare a drug carrier variety of molecules such as proteins, nucleotides and even plasmids. Some drugs are also formulated asliposomes to improve their therapeutic index, stability and compatability. The vesicular drug delivery systems such asliposomes, niosomes, transfersomes, and pharmacosomes were developed. In this paper main focus on liposomalclassification, various method of preparation, evaluation parameter , merits, recent status and scope