Mass-spectrometry In Stereoisomer Characterization - the Case of 1,3,4-trideoxy-3-fluoronojirimycins and 1,3,4-trideoxy-3-fluoromannojirimycins

The mass spectrometric characterization of stereoisomeric 1,3,4-trideoxy-3-fluoronojirimycins and 1,3,4-trideoxy-3-fluoromannojirimycins has been achieved by means of metastable ion studies. In particular, mass-analyzed ion kinetic energy spectroscopy performed on the electron-ionization-generated molecular species of the title compounds has led to an easy and unequivocal differentiation of the four stereoisomers under study, by their unusual diagnostic fragmentation mechanisms