A Study of Effects of Vitamin C & Vitamin E Supplementation in Hypertensive & Diabetics in Tertiary Care Hospital

Background: Antioxidants scavenge free radicals to reduce oxidative stress in diabetes and hypertension. Our aim of our study was use of vit-C and vit-E on blood glucose, glycosylated haemoglobulin, serum lipid levels in diabetic and hypertensive patients. Materials & Methods: This is a prospective interventional study in known Diabetic and Hypertensive subjects. The equal subjects (N=140 each) were divided into two groups, diabetic group (group I) and hypertensive group (group II). Each Group were divided into Control Group who received standard treatment of Diabetes with Oral Hypoglycaemic drugs & anti-hypertensive drugs (n=70) & Test Group which received supplementation with antioxidants tablet Limcee (Vitamin C) of 500 mg & Tablet Evion (Vitamin E) of 400 mg orally in addition to standard treatment for 12 weeks. Blood samples were collected before and after supplementation for 12 weeks, blood sugar, HbA1c, lipid profile and blood pressure were measured. Data collected analyzed by SPSS 22. P values of <0.05 was considered significant. Results: Total Number of subjects was 280, out of which 140 participants 65.7 % were males in test group and 34.2% were females. Maximum number (77.5%) of hypertensives in Test Group 1 & 34.2% were females.&nbsp