Diabetic retinopathy is most important diabetic complication and remains the primary cause of avoidable blindness in working-aged persons. As the global prevalence of diabetes mellitus continues to increase, diabetic retinopathy remains a principal cause of vision loss in several developed countries. Most favorable control of blood pressure, blood glucose, and possibly blood lipids remains the foundation for decrease of risk of retinopathy development. Novel approaches for DR treatment are intraocular steroid injection and anti-vascular endothelial growth-factor (VEGF) agents, are less damaging to the retina than are older treatments. This article will summarize key detection and management approaches for the complications of diabetes with ...