Assessing the Relationship of Vitamin D and Glycosylated Haemoglobin to Establish Better Therapeutic Guidelines in Type 2 Diabetes Mellitus

Type 2 diabetes mellitus affects millions of people worldwide. it is a disease considered a major public health problem in India. Vitamin D deficiency was found to be more prevalent in India despite having sunny weather. Its deficiency was found to be correlated with glycosylated hemoglobin. We conducted this study in an effort to better understand the relationship between vitamin D and glycosylated hemoglobin in non-obese. A total of 119 type 2 diabetes patients were recruited in this cross-sectional study. Patient details and biochemical parameters were collected. Participants were divided into groups with vitamin D deficiency 25(OH) D <20 ng/ml and without vitamin D deficiency 25(OH) D >20 ng/mL, Further subgrouping was done into male and female-only groups. Next, the subjects were divided into male and female groups according to their 25(OH)D levels. The finding showed a significantly higher level of HbA1c (8.02±0.35%) in the vitamin D deficiency group compared to (7.32±0.41%) without vitamin D deficiency (p <.001). And it was also true for creatinine (0.94±0.14 vs. 0.82±0.17) (p<.001) HbA1c and Fasting plasma glucose both were significant negatively correlated with vitamin D deficient group only (r = - 0.49, p <.001), (r = - 0.40, p = 0.001).&nbsp