Diagnosis dan Manajemen Sindrom Sjogren

Sindrom Sjogren (SS) merupakan penyakit autoimun yang menyerang kelenjar eksokrin (kelenjar lakrimal dan saliva), dengan manifestasi klinis berupa keratokonjungtivitis sika (mata kering), xerostomia (mulut kering), dan gejala ekstraglandular (artritis, vaskulitis, disfagia, dan lainnya). Etiologi SS sampai saat ini masih belum diketahui. Sering terjadi missed diagnosis karena keluhan tidak spesifik. Pemaparan komprehensif mengenai sejarah, epidemiologi, etiologi, imunopatologi, patofisiologi, manifestasi klinis, manifestasi laboratorium, kriteria diagnosis, terapi, dan prognosis penting untuk praktisi medis.Sjogren's syndrome (SS) is an autoimmune disease that attacts the exocrine glands (lacrimal and salivary glands), clinically manifests as keratoconjunctivitis sicca (dry eye), xerostomia (dry mouth), and extraglandular symptoms (arthritis, vasculitis, dysphagia, etc.). The etiology is still unknown. Missed diagnosis often occurs because of non-specific complaints. Comprehensive presentation of history, epidemiology, etiology, immunopathology, pathophysiology, clinical manifestations, laboratory manifestations, diagnostic criteria, treatment, and prognosis is important for medical practitioners