Dehydropeptide-based plasmonic lipogels as bionanosystems for controlled drug release

In this work, silica-coated gold nanoparticles and liposomes (storage units) were combined with dehydropeptide-based hydrogels as a proof-of-concept to afford peptide-based NIR light-responsive lipogels. Several liposomes compositions were assessed to study its influence on the final assembly properties. Gold nanospheres were used to assess the preparation method that enabled a closer proximity of the nanoparticles to the liposomes.Ministerio de Economía y Competitividad de España (PID2020-113704RB-I00), Xunta de Galicia (Centro Singular de Investigación de Galicia - Accreditation 2019-2022 ED431G 2019/06 and IN607A 2018/5), and European Union-ERDF (Interreg V-A - Spain-Portugal 0245_IBEROS_1_E, 0712_ACUINANO_1_E, and 0624_2IQBIONEURO_6_E, and Interreg Atlantic Area NANOCULTURE 1.102.531)