Add to ORKGAmphiphilic PEG derivatives with different structure and size have been investigated for preparation of micelles for amphotericin-B delivery. The PEG5kDa-cholanic based formulation was the best performing polymer as it displayed low toxicity, high amphotericin-B loading, high stability, and prolonged in vivo drug permanence. The biopharmaceutical performance of this formulation was superior to the positive control Fungizone
In this study, we report the synthesis of PDMAEMA-b-PCL-b-PDMAEMA via ATRP starting from two dibromi...
The present study describes the production and characterization of amphiphilic association systems f...
Li Zhou,1,* Peipei Zhang,1,* Zhuo Chen,1 Shaona Cai,2 Ting Jing,2 Huihui Fan,2 Fei Mo,2 Jiye Zhang,2...
A novel formulation for amphotericin B (AmB) delivery has been developed using micelle-forming 5 kDa...
A novel formulation for amphotericin B (AmB) delivery has been developed using micelle-forming 5 kDa...
Polymeric micelles prepared from a series of poly(ethylene glycol)-poly(lactide) (PEG-PLA) diblock c...
AbstractAmphotericin B (AmB), a poorly soluble and toxic antifungal drug, was encapsulated into poly...
The clinical application of amphotericin B (AmB), a broad spectrum antifungal agent, is limited by i...
Ying-Chen Chen,* Chia-Yu Su,* Hua-Jun Jhan, Hsiu-O Ho, Ming-Thau Sheu School of Pharmacy, College o...
In clinical studies, drugs with hydrophobic characteristic usually reflect low bioavailability, poor...
With the emergence of nanotechnology in drug delivery, colloidal systems and particularly polymeric ...
abstract: The current methods of drug delivery prove to have inefficiencies as far as drug administr...
Polymeric micelles based on HPMA [N-(2-hydroxypropyl) methacrylamide] polymers were recently evaluat...
AbstractPurposeAmphotericin B (AmB) is an effective anti-fungal and anti-leishmanial agent. However,...
Amphotericin B remains the drug of choice for the treatment of most of the systemic fungal infection...
In this study, we report the synthesis of PDMAEMA-b-PCL-b-PDMAEMA via ATRP starting from two dibromi...
The present study describes the production and characterization of amphiphilic association systems f...
Li Zhou,1,* Peipei Zhang,1,* Zhuo Chen,1 Shaona Cai,2 Ting Jing,2 Huihui Fan,2 Fei Mo,2 Jiye Zhang,2...
A novel formulation for amphotericin B (AmB) delivery has been developed using micelle-forming 5 kDa...
A novel formulation for amphotericin B (AmB) delivery has been developed using micelle-forming 5 kDa...
Polymeric micelles prepared from a series of poly(ethylene glycol)-poly(lactide) (PEG-PLA) diblock c...
AbstractAmphotericin B (AmB), a poorly soluble and toxic antifungal drug, was encapsulated into poly...
The clinical application of amphotericin B (AmB), a broad spectrum antifungal agent, is limited by i...
Ying-Chen Chen,* Chia-Yu Su,* Hua-Jun Jhan, Hsiu-O Ho, Ming-Thau Sheu School of Pharmacy, College o...
In clinical studies, drugs with hydrophobic characteristic usually reflect low bioavailability, poor...
With the emergence of nanotechnology in drug delivery, colloidal systems and particularly polymeric ...
abstract: The current methods of drug delivery prove to have inefficiencies as far as drug administr...
Polymeric micelles based on HPMA [N-(2-hydroxypropyl) methacrylamide] polymers were recently evaluat...
AbstractPurposeAmphotericin B (AmB) is an effective anti-fungal and anti-leishmanial agent. However,...
Amphotericin B remains the drug of choice for the treatment of most of the systemic fungal infection...
In this study, we report the synthesis of PDMAEMA-b-PCL-b-PDMAEMA via ATRP starting from two dibromi...
The present study describes the production and characterization of amphiphilic association systems f...
Li Zhou,1,* Peipei Zhang,1,* Zhuo Chen,1 Shaona Cai,2 Ting Jing,2 Huihui Fan,2 Fei Mo,2 Jiye Zhang,2...