Schizophrenia (SZ) and bipolar disorder (BPD) are two severe psychiatric diseases with a strong genetic component. In agreement with the 'continuum theory', which suggests an overlap between these disorders, the existence of genes that affect simultaneously susceptibility to SZ and BPD has been hypothesized. In this study we performed a 7.5 cM genome scan in a sample of 16 families affected by SZ and BPD, all originating from the same northeast Italian population. Using both parametric and non-parametric analyses we identified linkage peaks on four regions (1p, 1q, 4p and 15q), which were then subjected to a follow-up study with an increased marker density. The strongest linkage was obtained on chromosome 15q26 with a non-parametric linka...
Bipolar affective disorder is a heritable, relatively common, severe mood disorder with lifetime pre...
Much work has been done to identify susceptibility genes in schizophrenia and bipolar disorder. Seve...
There is substantial evidence for partial overlap of genetic influences on schizophrenia and bipolar...
Context Traditionally, the search for genes involved in predisposition to major psychoses has proce...
In this study, we report a genome scan for psychiatric disease susceptibility loci in 13 Scottish fa...
In order to identify susceptibility loci for schizophrenia (SZ) and bipolar disorder (BPD), we colle...
Recent family and genome-wide association studies strongly suggest shared genetic risk factors for s...
Recent genome-wide association studies (GWASs) investigating bipolar disorder (BD) have detected a n...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understandin...
There is substantial evidence for partial overlap of genetic influences on schizophrenia and bipolar...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding...
Recent findings from genetic epidemiology and from genome-wide association studies point strongly to...
Bipolar affective disorder is a heritable, relatively common, severe mood disorder with lifetime pre...
Much work has been done to identify susceptibility genes in schizophrenia and bipolar disorder. Seve...
There is substantial evidence for partial overlap of genetic influences on schizophrenia and bipolar...
Context Traditionally, the search for genes involved in predisposition to major psychoses has proce...
In this study, we report a genome scan for psychiatric disease susceptibility loci in 13 Scottish fa...
In order to identify susceptibility loci for schizophrenia (SZ) and bipolar disorder (BPD), we colle...
Recent family and genome-wide association studies strongly suggest shared genetic risk factors for s...
Recent genome-wide association studies (GWASs) investigating bipolar disorder (BD) have detected a n...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understandin...
There is substantial evidence for partial overlap of genetic influences on schizophrenia and bipolar...
Schizophrenia and bipolar disorder are two distinct diagnoses that share symptomology. Understanding...
Recent findings from genetic epidemiology and from genome-wide association studies point strongly to...
Bipolar affective disorder is a heritable, relatively common, severe mood disorder with lifetime pre...
Much work has been done to identify susceptibility genes in schizophrenia and bipolar disorder. Seve...
There is substantial evidence for partial overlap of genetic influences on schizophrenia and bipolar...