Prognostic Evaluation of the Donor Risk Index Among a Prospective Cohort of Italian Patients Undergoing Liver Transplantation

Vitale, A
D'Amico, FRANCESCO ENRICO
Gringeri, Enrico
Valmasoni, M
Pauletto, A
Bonsignore, Pasquale
Bassi, D
D'Amico, Fe
Polacco, M
Burra, Patrizia
Russo, FRANCESCO PAOLO
Angeli, Paolo
Poci, C
Feltracco, P
Romano, A
Cillo, Umberto

Open link

Publication date

January 2009

DOI

10.1016/j.transproceed.2009.03.097

Publisher

Elsevier BV

ISSN

0041-1345

Citation count (estimate)

Abstract

BACKGROUND/AIM: The definition of an extended criteria donor for orthotopic liver transplantation (OLT) remains controversial. The donor risk index (DRI) has become the main tool to define the marginality of hepatic grafts in the United States. The aim of this study was to prospectively evaluate the prognostic ability of DRI among a cohort of Italian patients undergoing OLT. METHODS: From December 2006 to March 2008, we prospectively calculated DRI in all consecutive cadaveric grafts. Recipient inclusion criteria were: adult patients with chronic liver disease enlisted for primary OLT. The primary end point was the incidence of primary graft dysfunction (PDF), namely, aspartate aminotransferase (AST) >2000 U/mL and prothrombin time <40% o...