Evaluation of ovalbumin nanocarriers to promote the vehiculization and antifungal properties of cinnamaldehyde in aqueous media
- Finos, Marianela B.
- Deseta, Maria Laura Griselda
- Sponton, Osvaldo Ernesto
- Frisón, Laura Noemí
- Musumeci, Matias Alejandro
- Santiago, Liliana Gabriela
- Perez, Adrián Alejandro
DOIAbstract
This paper is aimed to evaluate the vehiculization of trans-cinnamaldehyde (CIN) through the formation of complexes with ovalbumin (OVA) and heat-induced OVA nanoparticles (OVAn) to promote its application in aqueous media. OVAn production variables (pH and protein concentration) and some physicochemical features (size, surface hydrophobicity, and molecular weight) were explored. Complex formation was examined in terms of stoichiometric and thermodynamic (ΔH°, ΔS°, and ΔG°) parameters by applying fluorescence spectroscopy. Results revealed the strong influence of the OVA conformational state (native or aggregated) on CIN vehiculization. However, all systems showed similar encapsulation efficiencies (~62%). Besides, nanosized complexes were ...
Add to ORKG