Adjusting the surface hydrophilicity of poly(acrylates)

Cilj diplomskega dela je bil pripraviti poli(metakrilaten) material s kopolimerizacijo kombinacije hidrofilnih in hidrofobnih metakrilatov za povečanje hidrofilnost materiala na eni strani in izboljšanje selektivne vezave določenih beljakovinskih molekul na drugi strani. Polimerizirali smo monolite in membrane z različnim razmerjem metakrilatov butil metakrilat, 2-etilheksil metakrilat, lavril metakrilat in zamreževalom etilenglikol dimetakrilatom. Monomer BMA je najbolj hidrofilen LMA pa najmanj, zato smo povečevali delež BMA in zmanjševali delež LMA. Za polimerizacijo smo uporabili termični iniciator AIBN in foto iniciator I819. Ugotovili smo, da prisotnost kisika, uporaba iniciatorja in količina zamreževala vplivajo na potek proste radikalske polimerizacije. Dobljene produkte smo okarakterizirali z različnimi analiznimi metodami. S FT-IR spektroskopijo smo potrdili prisotnost glavnih funkcionalnih skupin v sintetiziranih polimerih. Z adsorpcijo/desorpcijo dušika z uporabo Brunauer-Emmett-Teller metode smo izmerili specifične površine materialov, ki so bile manjše od 0,5 m2/g. Z analizo za določanje stičnega kota pa smo ugotovili, da imajo pripravljeni materiali hidrofilno površino. Meritve stičnega kota so se zaradi spreminjanja molskega razmerja metakrilatov gibale med 57,8 ° in 92,7 °.The purpose of this thesis was to prepare a poly(methacrylate) material by copolymerizing combinations of hydrophilic and hydrophobic methacrylates to increase the material hydrophilicity on the one hand and improve the selective binding of certain protein molecules on the other. We polymerized monoliths and membranes with different ratio of methacrylates butyl methacrylate, 2-ethylhexyl methacrylate, lauryl methacrylate and crosslinker ethylene glycol dimethacrylate. BMA monomer is the most hydrophilic and LMA the least, so we increased the share of BMA and decreased the share of LMA. AIBN thermal initiator and I819 photo initiator were used for polymerization. We found out that the presence of oxygen, the use of the initiator and the amount of crosslinker affect the course of free radical polymerization. The obtained products were characterized by various analyses. With FT-IR spectroscopy we confirmed the presence of the main synthesized functional groups in polymers. Using Brunauer-Emmett-Teller porosimetry, we measured the specific surface areas of materials that were smaller than 0.5 m2/g. With contact angle determination analysis, we found out that the prepared material has a hydrophilic surface. The contact angle measurements varied between 57,8° and 92,7° due to the change in the molar ratio of methacrylates