Tuberculosis (TB), due to Mycobacterium tuberculosis infection, is still the principal cause of death caused by a single infectious agent. The balance between the bacillus and host defense mechanisms reflects the different manifestations of the pathology. Factors defining this variety are unclear and likely involve both mycobacterial and immunological components. Myeloid derived suppressor cells (MDSC) have been shown to be expanded during TB, but their role in human TB pathogenesis is not clear. We evaluated the frequency of circulating MDSC by flow-cytometry in 19 patients with active TB, 18 with latent TB infection (LTBI), and 12 healthy donors (HD) as control. Moreover, we investigated the capacity of MDSC to modulate the mycobactericid...
Increasing drug resistance and the lack of an effective vaccine are the main factors contributing to...
Tuberculosis (TB) is still the principal cause of death caused by a single infectious agent, and the...
One-third of humans carry Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB) whe...
Tuberculosis (TB), due to Mycobacterium tuberculosis infection, is still the principal cause of deat...
: Tuberculosis (TB), due to Mycobacterium tuberculosis infection, is still the principal cause of de...
Tuberculosis (TB) has tremendous public health relevance. It most frequently affects the lung and is...
Tuberculosis (TB) is still the principal cause of death caused by a single infectious agent, and the...
Tuberculosis (TB) is still the principal cause of death caused by a single infectious agent, and the...
Background: The immune mechanisms underlying the pathogenesis of tuberculosis (TB) need better under...
Myeloid-derived suppressor cells (MDSCs) represent an innate immune cell population comprised of imm...
BACKGROUND: In human blood, mucosal-associated invariant T (MAIT) cells are abundant T cells that re...
Tuberculosis (TB) has tremendous public health relevance. It most frequently affects the lung and is...
Tuberculosis remains a global health problem caused by infection with Mycobacterium tuberculosis. Nu...
BACKGROUND: In human blood, mucosal-associated invariant T (MAIT) cells are abundant T cells, which ...
Individuals exposed to Mycobacterium tuberculosis (Mtb) may be infected and remain for the entire li...
Increasing drug resistance and the lack of an effective vaccine are the main factors contributing to...
Tuberculosis (TB) is still the principal cause of death caused by a single infectious agent, and the...
One-third of humans carry Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB) whe...
Tuberculosis (TB), due to Mycobacterium tuberculosis infection, is still the principal cause of deat...
: Tuberculosis (TB), due to Mycobacterium tuberculosis infection, is still the principal cause of de...
Tuberculosis (TB) has tremendous public health relevance. It most frequently affects the lung and is...
Tuberculosis (TB) is still the principal cause of death caused by a single infectious agent, and the...
Tuberculosis (TB) is still the principal cause of death caused by a single infectious agent, and the...
Background: The immune mechanisms underlying the pathogenesis of tuberculosis (TB) need better under...
Myeloid-derived suppressor cells (MDSCs) represent an innate immune cell population comprised of imm...
BACKGROUND: In human blood, mucosal-associated invariant T (MAIT) cells are abundant T cells that re...
Tuberculosis (TB) has tremendous public health relevance. It most frequently affects the lung and is...
Tuberculosis remains a global health problem caused by infection with Mycobacterium tuberculosis. Nu...
BACKGROUND: In human blood, mucosal-associated invariant T (MAIT) cells are abundant T cells, which ...
Individuals exposed to Mycobacterium tuberculosis (Mtb) may be infected and remain for the entire li...
Increasing drug resistance and the lack of an effective vaccine are the main factors contributing to...
Tuberculosis (TB) is still the principal cause of death caused by a single infectious agent, and the...
One-third of humans carry Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB) whe...