Multifaceted demographic dynamics have shaped population growth in Mediterranean Europe, reflecting a metropolitan cycle from urbanization to re-urbanization. To assess the distinctive impact of economic downturns on population dynamics, the present study illustrates the results of an exploratory analysis that assesses urban expansion and rural decline at various temporal scales in Greece, a peripheral country in southeastern Europe. Statistical analysis based on multivariate exploratory techniques outlined the persistent increase of regional populations, evidencing the distinctive role of agglomeration/scale with urbanization and early suburbanization phases (1940-1980) and accessibility/amenities with late suburbanization and re-urbanizat...