Crosstalk between trophoblast and monocytes is essential for gestational success, and it can be compromised in congenital toxoplasmosis. Cell death is one of the mechanisms involved in the maintenance of pregnancy, and this study aimed to evaluate the role of trophoblast in the modulation of monocyte cell death in the presence or absence of Toxoplasma gondii infection. THP-1 cells were stimulated with supernatants of BeWo cells and then infected or not with T. gondii. The supernatants were collected and analyzed for the secretion of human Fas ligand, and cells were used to determine cell death and apoptosis, cell death receptor, and intracellular proteins expression. Cell death and apoptosis index were higher in uninfected THP-1 cells stimu...
International audienceInfection with Toxoplasma gondii has a major implication in public health. Tox...
Estradiol (E2) plays a crucial and intricate role during pregnancy to mediate several aspects of the...
Fig 2. This schematic overview suggests signaling pathways of apoptosis. Apoptosis is induced throug...
Crosstalk between trophoblast and monocytes is essential for gestational success, and it can be comp...
INTRODUCTION: The interaction between human extravillous trophoblasts and macrophages has an impo...
Macrophage migration inhibitory factor (MIF) is a potent pro-inflammatory cytokine, which mediates t...
SummaryObjectiveTo assess whether interferon gamma (IFN-γ) secreted by decidual natural killer (dNK)...
BACKGROUND: To analyze the effects of IL-10 on the HLA-G expression and the apoptosis of trophoblast...
AbstractIntroductionToxoplasma gondii is an intracellular parasite that causes severe disease when t...
Toxoplasma gondii is an opportunistic intracellular parasite that is highly prevalent in human and w...
Objective: To assess whether interferon gamma (IFN-γ) secreted by decidual natural killer (dNK) cell...
Autophagy is a process of cytoplasmic degradation of endogenous proteins and organelles. Although it...
Abstract Background Toxoplasma gondii, a single-celled parasite commonly found in mammals, has been ...
During pregnancy was observed a control in trophoblastic cell proliferation and apoptosis. However,...
INTRODUCTION: Macrophage migration inhibitory factor (MIF) participates in the immune response to T...
International audienceInfection with Toxoplasma gondii has a major implication in public health. Tox...
Estradiol (E2) plays a crucial and intricate role during pregnancy to mediate several aspects of the...
Fig 2. This schematic overview suggests signaling pathways of apoptosis. Apoptosis is induced throug...
Crosstalk between trophoblast and monocytes is essential for gestational success, and it can be comp...
INTRODUCTION: The interaction between human extravillous trophoblasts and macrophages has an impo...
Macrophage migration inhibitory factor (MIF) is a potent pro-inflammatory cytokine, which mediates t...
SummaryObjectiveTo assess whether interferon gamma (IFN-γ) secreted by decidual natural killer (dNK)...
BACKGROUND: To analyze the effects of IL-10 on the HLA-G expression and the apoptosis of trophoblast...
AbstractIntroductionToxoplasma gondii is an intracellular parasite that causes severe disease when t...
Toxoplasma gondii is an opportunistic intracellular parasite that is highly prevalent in human and w...
Objective: To assess whether interferon gamma (IFN-γ) secreted by decidual natural killer (dNK) cell...
Autophagy is a process of cytoplasmic degradation of endogenous proteins and organelles. Although it...
Abstract Background Toxoplasma gondii, a single-celled parasite commonly found in mammals, has been ...
During pregnancy was observed a control in trophoblastic cell proliferation and apoptosis. However,...
INTRODUCTION: Macrophage migration inhibitory factor (MIF) participates in the immune response to T...
International audienceInfection with Toxoplasma gondii has a major implication in public health. Tox...
Estradiol (E2) plays a crucial and intricate role during pregnancy to mediate several aspects of the...
Fig 2. This schematic overview suggests signaling pathways of apoptosis. Apoptosis is induced throug...