Gaba-producing lactococcus lactis strains isolated from camel’s milk as starters for the production of gaba-enriched cheese

The multiple health benefits attributed to the bioactive compound γ-aminobutyric acid (GABA) have prompted the food industry to investigate the development of functional GABA-rich foods via the use of GABA-producing microorganisms. This study reports the isolation of six GABA-producing Lactococcus lactis strains from camel’s milk; this is the first time that such microorganisms have been isolated from milk. The sequencing and in silico analysis of their genomes, and the characterisation of their technological and safety properties, confirmed their potential as starters. Experimental cheeses made with all six strains (individually) accumulated GABA at concentrations of up to 457 mg/kg. These GABA-producing L. lactis strains could be used as starter cultures for the manufacture of functional GABA-enriched cheeses that provide health benefits to consumers.This work was funded by the Spanish State Research Agency (AEI) and the European Regional Development Funds (FEDER) (AGL2016-78708-R, AEI/FEDER, UE); by the Plan for Science, Technology and Innovation of the Principality of Asturias 2018–2020, co-financed by FEDER (IDI/2018/000114, FICYT/FEDER, UE); and by the Spanish National Research Council (CSIC201870I091, CSIC)