Attacker-defender models help practitioners understand a network’s resistance to attack. An assailant interdicts a network, and the operator responds in such a way as to optimally utilize the degraded network. This thesis analyzes two network interdiction algorithms, Benders decomposition and a dual integer linear program approach, to compare their computational efficiency on the shortest path and maximum flow interdiction problems. We construct networks using two operationally meaningful structures: a grid structure designed to represent an urban transportation network, and a layered network designed to mimic a supply chain. We vary the size of the network and the attacker's budget and we record each algorithm’s runtime. Our results indic...