An in vitro study of the interaction of Sea-Nine((R)) with rat liver mitochondria

The interactions of the antifouling compound Sea-Nine with rat liver mitochondria have been studied. The results indicate that low doses of this compound inhibit adenosine 5'-triphosphate (ATP) synthesis. Further investigations indicate that ATP synthesis inhibition should be due to an interaction of Sea-Nine with the succinic dehydrogenase in the mitochondrial respiratory chai