Chlamydia trachomatis is the most common cause of bacterial sexually transmitted infections and causes serious reproductive tract complications among women. The limitations of existing oral antibiotics and treatment of antimicrobial resistance require alternative treatment options. We are proposing, for the first time, the natural polyphenol resveratrol (RES) in an advanced delivery system comprising liposomes incorporated in chitosan hydrogel, for the localized treatment of C. trachomatis infection. Both free RES and RES liposomes-in-hydrogel inhibited the propagation of C. trachomatis in a concentration-dependent manner, assessed by the commonly used in vitro model comprising McCoy cells. However, for lower concentrations, the anti-chlamy...
Resveratrol (RSV) is a phytoceutical polyphenolic compound exhibiting a well evidenced wide range of...
Vulvovaginal candidiasis (VVC) is a widely spread fungal infection that causes itching, pain and inf...
This is the published version. Copyright © 2014, American Society for Microbiology. All Rights Reser...
Chlamydia trachomatis is the most common cause of bacterial sexually transmitted infections and caus...
Chlamydia trachomatis is the most common cause of bacterial sexually transmitted infections and caus...
Administering drug formulations to the vagina is a challenge since the vagina possesses “self-cleani...
The natural polyphenol resveratrol (RES) has shown great potential as an antimicrobial, including a...
Natural polyphenols, such as resveratrol (RES) or epicatechin (EPI), are attractive for treatments o...
Chlamydia trachomatis (C. trachomatis) is an obligate intracellular bacterium linked to ocular and u...
Vulvovaginal candidiasis (VVC) is a widely spread fungal infection that causes itching, pain and inf...
The vaginal inflammation and infection are one of the major female health issues, and unfortunately ...
Successful treatment of skin infections requires eradication of biofilms found in up to 90 % of all ...
Vaginal infections are common in women of all ages and proper treatment is essential. The vaginal ro...
Chlamydiae are obligate intracellular Gram-negative bacteria with a unique biphasic developmental cy...
Chlamydia trachomatis (C. trachomatis) is an obligate intracellular bacterium linked to ocular and u...
Resveratrol (RSV) is a phytoceutical polyphenolic compound exhibiting a well evidenced wide range of...
Vulvovaginal candidiasis (VVC) is a widely spread fungal infection that causes itching, pain and inf...
This is the published version. Copyright © 2014, American Society for Microbiology. All Rights Reser...
Chlamydia trachomatis is the most common cause of bacterial sexually transmitted infections and caus...
Chlamydia trachomatis is the most common cause of bacterial sexually transmitted infections and caus...
Administering drug formulations to the vagina is a challenge since the vagina possesses “self-cleani...
The natural polyphenol resveratrol (RES) has shown great potential as an antimicrobial, including a...
Natural polyphenols, such as resveratrol (RES) or epicatechin (EPI), are attractive for treatments o...
Chlamydia trachomatis (C. trachomatis) is an obligate intracellular bacterium linked to ocular and u...
Vulvovaginal candidiasis (VVC) is a widely spread fungal infection that causes itching, pain and inf...
The vaginal inflammation and infection are one of the major female health issues, and unfortunately ...
Successful treatment of skin infections requires eradication of biofilms found in up to 90 % of all ...
Vaginal infections are common in women of all ages and proper treatment is essential. The vaginal ro...
Chlamydiae are obligate intracellular Gram-negative bacteria with a unique biphasic developmental cy...
Chlamydia trachomatis (C. trachomatis) is an obligate intracellular bacterium linked to ocular and u...
Resveratrol (RSV) is a phytoceutical polyphenolic compound exhibiting a well evidenced wide range of...
Vulvovaginal candidiasis (VVC) is a widely spread fungal infection that causes itching, pain and inf...
This is the published version. Copyright © 2014, American Society for Microbiology. All Rights Reser...